532nm绿激光全视网膜光凝术联合中药治疗视网膜中央静脉阻塞的疗效分析  

Efficacy analysis on 522 nm green laser panretinal photocoagulation combined with traditional Chinese medicine for treatment of central retinal vein occlusion

作　　者：魏光杰[1] 何佃菊[1] 

机构地区：[1]莱芜市人民医院眼科,山东省莱芜市271100

出　　处：《眼科新进展》2013年第10期974-976,共3页Recent Advances in Ophthalmology

摘　　要：目的探讨532 nm绿激光全视网膜光凝术联合中药治疗视网膜中央静脉阻塞(central retinal vein occlusion,CRVO)的临床疗效。方法选取我院2011年2月至2012年3月收治的86例(100眼)缺血型CRVO患者,随机分为两组,对照组(43例,48眼)单纯给予532 nm绿激光全视网膜光凝术治疗,观察组(43例,52眼)在对照组基础上联合中药进行治疗。随访期末采用眼底镜及眼底荧光血管造影观察患者眼底改变情况,采用国际标准视力表检查患者治疗前后视力,同时使用光学相干断层扫描仪检查患者治疗前后的黄斑厚度。结果观察组治愈23眼,有效26眼,无效3眼,总有效率为94.23%;对照组治愈18眼,有效22例,无效8眼,总有效率为83.33%;两组患者总有效率差异有统计学意义(P<0.05)。两组治疗后视力比较,观察组视力好于对照组,差异有统计学意义(P<0.05)。对照组和观察组患者治疗前黄斑厚度分别为(590.23±44.15)μm、(594.55±42.74)μm,差异无统计学意义(P>0.05);治疗后黄斑厚度分别为(365.44±35.26)μm、(215.86±38.75)μm,较治疗前均降低,差异均有统计学意义(均为P<0.05);两组治疗后黄斑厚度比较,观察组低于对照组,差异有统计学意义(P<0.05)。结论 532 nm绿激光全视网膜光凝术联合中药治疗缺血型CRVO疗效显著,可显著改善患者的视功能,提高患者的生活质量。Objective To discuss clinical efficacy of treatment of central retinal vein occlusion with 522 nm green laser panretinal photocoagulation combined with tra- ditional Chinese medicine. Methods Eighty-six patients of ischemic CRVO, who were treated in the hospital from February 2011 to march 2012 ,were selected and randomly di- vided into two groups：the control group（43 cases and 48 eyes） ,only treated with 522 nm green laser panretinal photocoagulation; the observation group （ 43 cases and 52 eyes）, treated with 522 nm green laser panretinal photocoagulation combined with traditional Chinese medicine. In the end of follow-up period,ophthalmofundoscope and fluorescence fundus angiography were used to observe the changes of patients＇ fundus, standard visual acuity chart was adopted to check patients＇ preoperative and postoperative vision and meanwhile, optical coherence tomo^Talahy （OCT） was used to examine the thickness ofmacula lutea before and after therapy. Results In observation group, the total effective rate reached 94.23%, with curing 23 eyes ,25 effective and 3 ineffective;while,in control group,the total effective rate reached 83.35%, 18 eyes cured,22 effective and 8 ineffective. And the differences of total effective rate were of statistical significance （P 〈 0.05 ）. The vision in observa- tion group was better than that in control group after the therapy and differences were of statistical significance （P 〈 0.05 ）. Before the therapy, thickness of macula hitea in control group and observation group was （590.23 ± 44.15 ） μm and （594.55 ± 42.74） μm, respectively, and differences were of no statistical significance（P 〉0. 05 ）. While after the therapy,thickness of macula lutea in control group and observation group was （ 365.44 ± 35.25） μm and （215.85 ± 38.75 ） μm, respectively and a de- crease was indicated. And differences were of statistical significance （P 〈 0.05 ）. The comparison of thickness of macula lutea between two groups suggested t

关 键 词：视网膜中央静脉阻塞 视网膜光凝 中药 

分 类 号：R774.1[医药卫生—眼科]