人群乙型肝炎血清学标志物模式的特征  

Characteristics of the model for serological markers of human hepatitis B virus

作　　者：储凯[1] 许可[1] 秦圆方[1] 张艺飓[1] 朱凤才[1] 

机构地区：[1]江苏省疾病预防控制中心急性传染病防制所,江苏南京210009

出　　处：《现代预防医学》2013年第18期3490-3493,共4页Modern Preventive Medicine

摘　　要：目的探索本地区16~60周岁人群乙型肝炎血清学标志物模式的特征,完善乙型肝炎流行病学资料。方法无菌采集5 ml新鲜人静脉血,采用ELISA试剂盒法完成乙型肝炎血清学标志物的检测,统计检测结果,使用Stata9.0软件进行分析。结果该人群HBsAg携带率为5.6%,非妊娠者出现HBVM模式17种,常见模式（构成比﹥1%）7种,妊娠女性HBVM模式6种（构成比﹥1%）。常见模式及16~30年龄段常见模式中男女构成比存在统计学差异（P﹤0.05）,妊娠女性与16~40年龄段非妊娠女性的模式1构成比亦存在统计学差异（P﹤0.05）。结论模式5、模式1和模式2成为常见模式中影响男女构成比的重要因素。OBJECTIVE Characteristics of the model for serological markers of hepatitis B virus in men and women between the age of 16 and 60 from this region were explored to improve the epidemiological data of hepatitis B. METHODS 5 ml of fresh venous blood was collected in aseptic conditions. Serological markers of hepatitis B virus in the blood samples were detected by using an ELISA kit, followed by statistical analyses performed by the Stata 9.0 software. RESULTS HBsAg-positive rate among the tested subjects was 5.6%. 17 HBVM models were identified among non-pregnant subjects, with 7 common models （constituent ratio 〉 1% ） and 6 female HBVM models （constituent ratio 〉 1%）. Statistical differences in constituent ratio of male and female existed between common models and those for 16-30 years old subjects （P 〈 0.05）. Constituent ratio of model 1 in pregnant female and non-pregnant female between the age of 16 and 40 also exhibited statistical differences （P 〈 0.05）. CONCLUSION Model 5, model 1, and model 2 are the key factors influential to the constituent ratio of male and female in common models.

关 键 词：乙型肝炎血清学标志物 模式 构成比 

分 类 号：R575.1[医药卫生—消化系统]