老年心房颤动患者合并脑血管病危险因素研究  

Risk factors for cerebrovascular diseases in elderly patients with atrial fibrillation

作　　者：乔秋博[1] 毕齐[1] 

机构地区：[1]首都医科大学附属北京安贞医院神经内科北京市心肺血管疾病研究所,100029

出　　处：《中华老年心脑血管病杂志》2013年第9期909-911,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的研究老年心房颤动(房颤)患者合并脑血管病的危险因素。方法选择房颤患者16 885例,根据年龄分为老年组7254例(年龄≥65岁),对照组9631例(年龄<65岁),对比分析老年房颤患者合并脑血管病的危险因素。结果房颤患者合并脑血管病的总患病率为9.4%。老年组脑血管病患病率明显高于对照组(14.4%vs5.6%,P<0.01),老年组合并脑血管病危险因素中,男性比例明显低于对照组,高血压、糖尿病、高同型半胱氨酸血症、冠心病比例明显高于对照组(P<0.05,P<0.01)。logistic回归分析,年龄、高血压、糖尿病、高脂血症、高同型半胱氨酸血症为房颤合并脑血管病的独立危险因素(P<0.01)。结论老年心房颤动患者合并脑血管病患病率明显高于非老年心房颤动患者,年龄、高血压、糖尿病、高脂血症、高同型半胱氨酸血症是心房颤动合并脑血管病的独立危险因素。Objective To study the risk factors for cerebrovascular diseases in elderly patients with atrial fibrillation （AF）. Methods A total of 16 885 AF patients were divided into ;65 years old group （n=7254） and ; 65 years old group （n=9631）. Risk factors for cerebrovascular diseases were compared and analyzed. Results The total incidence of cerebrovascular diseases was 9.4% in elderly AF patients and significantly higher in ; 65 years old group than in ; 65 years old group （14.4% vs 5.6% ,P〈0. 01）. The risk factors for hypertension,diabetes mellitus （DM） ,hyperhomocysteinemia and coronary heart disease were significantly more in ; 65 years old group than in ;65 years old group （P〈0.05 ,P〈0.01）. Logistic regression analysis showed that age, hypertension,DM, hyperlipidemia, hyperhomocysteinemia were the independent risk factors for cerebrovascular diseases in elderly AF patients （P〈0. 01）. Conclusion The incidence of cerebrovascular diseases is significantly higher in elderly AF patients than in non-elderly AF patients. Age,hypertension, DM, hyperlipidemia, hyperhomocysteinemia are the independent risk factors for cerebrovascular diseases in elderly AF patients.

关 键 词：心房颤动 脑血管障碍 高血压 高同种半胱氨酸血症 糖尿病 危险因素 

分 类 号：R541.75[医药卫生—心血管疾病]