重症急性胰腺炎患者合并胰腺感染相关影响因素分析  

Related factors for complicate pancreatic infections in severe acute pancreatitis patients

作　　者：王巍 刘晓宇[2] 

机构地区：[1]青海省第五人民医院外科,青海西宁810000 [2]青海省中医院功能科,青海西宁810000

出　　处：《中华医院感染学杂志》2013年第17期4163-4164,共2页Chinese Journal of Nosocomiology

摘　　要：目的探讨重症急性胰腺炎合并胰腺感染的相关影响因素,为感染的预防提供依据。方法选取2000年1月-2012年12月进行诊治的86例重症急性胰腺炎患者为研究对象,将其中胰腺感染的发生率进行统计,并将其中不同疾病及治疗与胰腺感染发生率进行比较。结果胰腺坏死程度三期、肠功能障碍时间>5d、功能不全器官数目>2个、存在低氧血症、手术时间>7d、全胃肠外营养时间>20d及进行机械通气者的胰腺感染率分别为52.63%、46.43%、55.00%、47.62%、86.36%、55.56%和44.44%,胰腺坏死程度一期与二期、手术时间>7d、全胃肠外营养时间>20d、进行机械通气者感染率分别为86.36%、55.56%、32.00%,差异均有统计学意义(P<0.05)。结论重症急性胰腺炎合并胰腺感染的相关影响因素主要包括疾病本身及治疗干预措施等方面。OBJECTIVE To study the related influencing factors of severe acute pancreatitis complicated with pan-creatic infections. METHODS Totally 86 patients with severe acute pancreatitis and diagnosed, treated in our hospital from January 2010 to December 2012 were selected as research objects,then the pancreatic infection rate of allpatients was analyzed,and the pancreatic infection rate of patients with different disease situation and treatment related situation were compared. RESULTS The pancreatic infection rates of patients with pancreatic necrosis thirdstage,intestinal dysfunction time〉5d,organ dysfunction number〉2,hypoxemia,within 7 days of operation,TNP〉20d and mechanical ventilation were 52.63%,46. 43%,55. 00%,47.62%, 86.36%,55. 56%, and 44. 44 % , andthey were higher than 31. 58% ,34. 48% ,32. 76% ,31. 82% ,33. 85%,20. 31 % ,32. 35% , and 32. 00% of patientswith first and second stage, intestinal dysfunction time≤5 d,organ dysfunction number≤2 , without hypoxemia,without 7 days of operation,TNP〉20 d and without mechanical ventilation, all the differences were staisticallysignificant （all P〈0. 05）. CONCLUSION The related influence factors of severe acute pancreatitis complicated withpancreatic infection mainly include disease itself and treatment measures.

关 键 词：重症急性胰腺炎 胰腺感染 影响因素 

分 类 号：R576[医药卫生—消化系统]