子宫内膜癌附件转移的高危因素分析  

A high-risk-factor analysis of adnexal metastasis of endometrial carcinoma

作　　者：叶敏娟[1] 麦赞[1] 叶辉霞[1] 杨越波[1] 

机构地区：[1]中山大学附属第三医院妇产科,广州510630

出　　处：《新医学》2013年第9期629-631,共3页Journal of New Medicine

摘　　要：目的探讨子宫内膜癌附件转移的高危因素。方法收集130例子宫内膜癌患者的临床资料,分析年龄、绝经、病理类型、组织学分级、宫颈侵犯、肌层浸润深度、淋巴结转移、腹水细胞学等与附件转移的关系。结果 130例中,发生附件转移8例(6.2%)。年龄(≤45岁或>45岁)、绝经与否的子宫内膜癌患者附件转移的发生率比较差异无统计学意义(P>0.05)。子宫内膜样腺癌与非子宫内膜样腺癌,各组织学分级间,肌层浸润深与浅,宫颈受侵与否的附件转移发生率比较差异均无统计学意义(P>0.05)。有淋巴结转移、腹水细胞学阳性者的附件转移发生率较高(P均<0.05)。进一步多元Logistic回归分析显示,仅腹水细胞学阳性是子宫内膜癌患者附件转移的独立高危因素(P<0.01)。结论子宫内膜癌的附件转移与腹水癌细胞阳性或伴有淋巴结转移有关,腹水细胞学阳性是附件转移的独立高危因素。Objective To study the high risk factors of adnexal metastasis of endometrial carcinoma. Methods Retrospective analysis was used for 130 cases of endometrial carcinoma. The correlations of adnexa metastasis and age, menopause, pathological types, histological grades, cervical invasion, muscular invasion depth, pelvic lymphatic metastasis and peritoneal cytology were analysis respectively. Results In 130 cases of endometrial carcinoma, 8 cases had adnexal metastasis （6. 2% ）. The difference of the different age groups （ ~〈45years old or 〉 45years old） who were endometrial carcinoma with adnexal metastasis was not statistically significant （ P 〉 0. 05 ）. Neither in patients who have the menopause or not （ P 〉 0. 05 ）. The difference of ad- nexal metastasis rates in different pathologic types was not statistically significant （ P 〉 0. 05 ）. The difference was not statistically significant （ P 〉 0. 05 ） for the adnexal metastasis rates of different degree myometrial inva- sion depth, neither was the difference of different histologic grades （ G1, G2, G3 ） nor the difference of cervi- cal invasion or not. The adnexal metastasis rates of whom with lymph node metastasis and positive peritoneal cy- tology were higher than whom with not lymph node metastasis and negtive peritoneal cytology, the differences were statistically significant （ P 〈 0. 05, P 〈 0. 01 ）. Logistic regression analysis further showed that only positive peritoneal cytology was an independent risk factor for the adnexal metastasis （ P 〈 0. 01 ）. Conclusion Adnexal metastasis is related to lymph node metastasis and espeeially to the positive peritoneal cytology.

关 键 词：子宫内膜癌 附件转移 高危因素 

分 类 号：R737.33[医药卫生—肿瘤]