MR波谱对脑胶质瘤术后放疗后复发的鉴别诊断价值  

The Differential Diagnostic Value of MR Spectroscopy in the Recurrence of Brain Glioma after Radiotherapy

作　　者：刘岚[1] 徐仁根[1] 王索宇[1] 周雪春[1] 孙美[1] 周锋江[1] 

机构地区：[1]江西省肿瘤医院,330029

出　　处：《实用癌症杂志》2013年第5期489-491,共3页The Practical Journal of Cancer

基　　金：江西省卫生厅科技计划项目(20111094)

摘　　要：目的探讨MR波谱(MRS)对脑胶质瘤术后放疗后复发的鉴别诊断价值。方法应用GE Singa EXCITE1.5T HD高分辨磁共振检查仪,对50例脑胶质瘤术后放疗后常规MR检查出现新强化灶的患者行1H-MRS,经再次手术、临床及MR随访综合诊断肿瘤复发23例,放射性脑坏死27例。结果肿瘤复发组(23例)病变强化灶中Cho/NAA、Cho/Cr比值高于放射性脑坏死组(27例),两者比较有统计学差异(P<0.01),而Cho、NAA、Cr含量及NAA/Cr比值两组比较差异无统计学意义(P>0.05)。结论脑胶质瘤术后复发灶的Cho/NAA、Cho/Cr指标明显高于放射性脑坏死,对其鉴别诊断具有重要价值。Objective To evaluate the differential diagnostic value of MR spectroscopy in the recurrence of brain glioma after radiotherapy. Methods 1 H-MRS examinations were performed with GE Singa EXCITE 1.5T HD MR system on 50 patients with glioma, who appeared recurrent contrast-enhancing masses on conventional MR after operation and radiation. 23 cases were fi- nally diagnosised as tumor recurrence through the comprehensive diagnosis and 27 cases as brain radiation necrosis. Results Cho/NAA,Cho/Cr of the tumor recurrence group were higher than those of the radiation necrosis group, the difference were statis- tically significant（P 〈 0.01 ）. There were no significant difference of Cho, NAA, Cr and NAA/Cr between the 2 groups （P 〉 0.05 ）. Conclusion Cho/NAA and Cho/Cr are higher in recurrent lesions than those of radiation necrosis ,which are valuable for the differential diagnosis.

关 键 词：脑胶质瘤 术后 放射治疗 MR波谱 复发 脑坏死 

分 类 号：R739.41[医药卫生—肿瘤]