艾滋病-痴呆综合征一例  

AIDS-dementia syndrome:a case report

作　　者：杨静[1] 李世平[1] 李震中[1] 

机构地区：[1]河北医科大学第二医院神经内科,河北省神经病学重点实验室,石家庄050000

出　　处：《脑与神经疾病杂志》2013年第5期373-376,共4页Journal of Brain and Nervous Diseases

基　　金：国家自然科学基金项目(30600082)

摘　　要：目的观察1例艾滋病-痴呆综合征患者的临床表现与影像学资料,为早期诊断提供临床证据。方法收集该病人的病史及我院住院治疗期间的体格检查、影像学检查和实验室检查。结果本病例亚急性发病,常规抗病毒治疗症状有所好转。头颅MRI显示两侧基底节区、胼胝体体部左份、右侧额叶、两侧穹窿、小脑蚓部见大片状长T1长T2高FLAIR异常信号,边界欠清楚,信号欠均匀,侧脑室扩张及海马萎缩。结论中青年人出现的快速进展性痴呆,且头颅MRI出现脑萎缩和弥漫性异常信号时,应考虑到艾滋病感染的可能性。Objective Observed a cases of HIV/AIDS-dementia syndrome patient,and improved the understanding of the clinical imaging and performance.Methods Collected the patient＇s history and in our hospital inpatient treatment of the physical examination,imaging examination and laboratory tests,then summarized the characteristics of the disease.Results The symptoms improved after conventional antiviral treatment.MRI showed patchy abnormal signal in the basal ganglia,the left part of corpus callosum body,the right of frontal lobe,the fomix and cerebellar vermis; moreover,it included ventricular expansion and hippocampal atrophy.Conclusion We should take into account the possibility of special infected,when young people are in dementia whose MRI show brain atrophy and diffuse abnormal signal.

关 键 词：艾滋病 脑病 磁共振 

分 类 号：R744[医药卫生—神经病学与精神病学]