2000～2012年期间华西医院甲状腺疾病构成的变化分析  

Analysis on Change of Constitution in Thyroid Diseases of West China Hospital Between 2000 and 2012

作　　者：邹秀和[1] 孙映荷[1] 朱信心[1] 黄秋实[1] 李志辉[1] 龚日祥[1] 苟菊香[1] 刘枫[1] 杜镇鸿[1] 朱精强[1] 

机构地区：[1]四川大学华西医院甲状腺乳腺外科,四川成都610041

出　　处：《中国普外基础与临床杂志》2013年第9期987-991,共5页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的探讨2000～2012年期间华西医院行初次手术治疗的甲状腺疾病的构成变化，为临床工作提供参考。方法回顾性分析2000～2012年期间华西医院行初次手术治疗的甲状腺疾病患者的临床资料，包括性别、年龄及病理学诊断，进行统计学分析。结果共纳入了9642例甲状腺疾病患者，男1893例，女7749例，男：女=1：4．09。男性患者中甲状腺癌的比例高于女性（P=0．02）。其中，〈45岁男性患者中甲状腺癌的比例高于女性（P〈0．01），而≥45岁男性和女性患者甲状腺癌的比例比较差异无统计学意义（P=0．90）。2000～2012年期间，甲状腺癌尤其是甲状腺乳头状癌的比例大体呈增高趋势；桥本甲状腺炎的比例及其中合并甲状腺癌的比例均大体呈增高趋势；结节性甲状腺肿的比例呈先上升后下降趋势；甲状腺腺瘤的比例大体呈下降趋势。结论近年来，行手术治疗的甲状腺疾病中甲状腺癌特别是甲状腺乳头状癌的比例大体呈增高趋势，需予以足够的重视。Objective To explore the change of constitution in thyroid diseases of West China Hospital between 2000 and 2012, in order to provide clinical evidence. Methods Clinical data, including gender, age, and pathological diagnosis of patients with thyroid disease who underwent primary thyroid surgery in our hospital from 2000 to 2012 were collected retrospectively and analyzed statistically. Results A total of 9 642 patients were enrolled, including 1 893 male patients and 7 749 female patients. The ratio of male to female patients was I to 4. 09. In male patients, the proportion of thyroid carcinoma were significantly higher than those of female group （P=0.02） ; in male patients younger than 45 group, the proportion of thyroid carcinoma were significantly higher than those of female group （P〈 0. 01）. There was no statistical difference on the proportion between male and female patients older than 45 group （P=0.90）. Proportion of thyroid carcinoma, especially proportion of papillary thyroid carcinoma （PTC） increased in general. Proportion of Hashimoto thyroiditis （HT） increased in general too. HT with thyroid carcinoma accounted for an increasing proportion of all patients with HT. Proportion of nodular goiter （NG） increased at first and then declined. Proportion of thyroid adenoma （TA） decreased on the whole. Conclusions Proportion of thyroid carcinoma, especially proportion of PTC increase in recent years on the whole in patients underwent surgery. All these changes need to be given sufficient attention.

关 键 词：甲状腺疾病 甲状腺癌 比例 变化 

分 类 号：R736.1[医药卫生—肿瘤]