速效救心丸治疗急性进展性脑梗死的疗效及其对患者血清hs-CRP水平的影响  被引量:4

Efficacy of Suxiaojiuxin pills in treatment of acute progressive cerebral infarction and their effects on serum high-sensitivity C-reactive protein

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作  者:张德华[1] 

机构地区:[1]泰安市第一人民医院,山东泰安271000

出  处:《山东医药》2013年第35期39-41,共3页Shandong Medical Journal

基  金:泰安市科技发展计划项目(20123044)

摘  要:目的观察速效救心丸治疗急性进展性脑梗死的临床疗效及其对患者血清超敏C-反应蛋白(hs-CRP)水平的影响。方法将104例急性进展性脑梗死患者随机分为治疗组和对照组,对照组常规治疗,治疗组常规治疗基础上应用速效救心丸2周。两组在治疗前及治疗后第7、14天分别进行临床神经功能缺损程度评分(NIHSS评分),检测血清hs-CRP水平,治疗前后检查动态心电图。结果治疗后14 d时,与对照组相比,治疗组NIHSS评分及血清hs-CRP水平均低(P均<0.01)。治疗组总有效率为84.6%,对照组为55.8%,两组比较,P<0.01。治疗组12例动态心电图改善,对照组3例。结论速效救心丸能改善进展性脑梗死患者临床神经功能缺损程度,改善临床预后,并降低hs-CRP水平。Objective To observe the clinical efficacy of Suxiaojiuxin pills in treatment of acute progressive cerebral infarction and their effects on the serum high-sensitivity C-reactive protein (hs-CRP). Methods Totally 104 patients with acute progressive cerebral infarction were randomly divided into the treatment group and the control group. Patients in the control group were given routine treatment, while patients in the treatment group were given Suxiaojiuxin pills besides rou- tine treatment for 2 weeks. The NIHSS scores, serum levels of hs-CRP and Holter monitoring were observed to evaluate the efficacy of both groups before treatment and on the 7th, 14th d after treatment. Results After treatment for 14 d, com- pared with the control group, NIHSS scores and serum level of hs-CRP in the treatment group decreased ( all P 〈 0.01 ) ; the total effective rate was 84.6% in the treatment group and 55.8% in the control group, and there were significant differ- ences between the treatment and control groups (P 〈 0.01 ). Twelve cases of the treatment group in Hoher monitoring were significantly improved, but 3 cases in the control group. Conclusion Suxiaojiuxin pills have remarkable effect on patients with acute progressive cerebral infarction in the neurological impairment, improve the clinical prognosis and effectively re- duce the level of hs-CRP.

关 键 词:速效救心丸 脑梗死 超敏C-反应蛋白 神经功能缺损程度评分 

分 类 号:R743.32[医药卫生—神经病学与精神病学]

 

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