超声法提取补虚颗粒中阿魏酸的正交试验研究  

Optimization of Ultrasonic Extraction of Ferulic Acid from Buxu Granules by Orthogonal Design

作　　者：陈琴华[1,2] 熊琳[1,2] 李鹏[1,2] 余飞[3] 

机构地区：[1]湖北医药学院附属东风医院药学部,湖北十堰442008 [2]湖北医药学院药物分析与筛选研究所 [3]湖北医药学院药学院

出　　处：《中国药师》2013年第9期1302-1304,共3页China Pharmacist

基　　金：湖北省教育厅科研研究计划项目(编号:D20122401;B20122424);湖北省卫生厅青年科技人才项目(编号:QJX2012-45)

摘　　要：目的:对超声法提取补虚颗粒中阿魏酸的工艺进行优化。方法:采用正交试验设计,利用超声法提取补虚颗粒中阿魏酸,考察了超声时间、液料比、温度和功率4影响个因素。结果:补虚颗粒中阿魏酸的优化提取条件为提取固液比为1∶30,超声时间为20 min,温度为50℃,超声功率为60 W。结论:该提取条件合理,阿魏酸提取效率高。Objective： To optimize the ultrasonic extraction technology of ferutic acid from Buxu granules. Method： Felic acid was extracted by ultrasonic method. Using the ultrasonic time, solid-liquid ratio, temperature and extraction power as the influencing factors, the process was optimized by orthogonal design. Result： The optimal conditions for the extraction process of Buxu granules were as follows ： solid-liquid ratio was 1 ： 30, the ultrasonic time was 20min with the ultrasonic power of 60W and the temperature of 50℃. Conclusion： The optimized extraction is rational and efficient.

关 键 词：补虚颗粒 阿魏酸 正交试验 超声法 

分 类 号：R284.2[医药卫生—中药学]