功能性消化不良患者胃电图与胃排空检测分析  

Detection and analysis of the electrogastrogram and gastric emptying in functional dyspepsia patients

作　　者：马刚[1] 戴伟杰[1] 

机构地区：[1]南京医科大学附属淮安第一医院消化科,江苏淮安223300

出　　处：《中国医师进修杂志》2013年第28期34-36,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的探讨功能性消化不良（FD）患者胃电图与胃排空的相关性及影响因素。方法使用Polygra／ID四导胃电分析系统和不透x线标记物法测定51例FD患者的胃电活动和餐后5h的胃排空情况。结果FD患者胃排空异常占31．4％（16／51），胃电图异常占72．5％（37，51）。胃电图正常患者与胃电图异常患者胃排空率比较差异无统计学意义（P〉0．05）。当胃排空和胃电图异常时，患者胃电节律紊乱，主频正常，部分患者合并餐后主功率不增加。轻、中及重度症状患者胃排空率比较差异无统计学意义（P〉0．05）；重度症状患者胃电图异常率较轻、中度症患者组明显增高[92．9％（13／14）比62．5％（10／16）、66．7％（14／21）]，差异有统计学意义（P〈0．05），轻度与中度症状患者胃电图异常率比较差异无统计学意义（P〉0．05）。幽门螺杆菌（Hp）阳性患者与Hp阴性患者的胃排空率比较差异无统计学意义（P〉0．05），Hp阳性患者胃电图异常率高于Hp阴性患者[90．0％（18／20）比61．3％（19／31）]，差异有统计学意义（P〈0．05）。有、无活动性胃炎患者的胃电图异常率及胃排空率比较差异均无统计学意义（P〉0．05）。结论胃电图异常在FD的发病中有一定意义；胃排空延缓与胃电图异常无明显联系；重度症状患者和Hp阳性患者胃电图异常率明显增高；有或无活动性胃炎与胃电活动及胃排空无明显相关性。Objective To investigate the correlation between electrogastrogram and gastric emptying in functional dyspepsia （FD） patients. Methods Fifty-one patients with FD were detected by polygraf ID 4-channel eleetrogastrogram（EGG） analysis system and solid radiopaque marker 5 h after a solid meal. Results 31.4% （ 16/51 ） patients showed delayed gastric emptying（GE ）, and 72.5%（37/51 ） patients showed abnormal EGG. The rate of GE between normal EGG patients and abnormal EGG patients had no significant differenee（P 〉 0.05 ）. In patients who had both abnormal EGG and delayed GE, EGG abnormality mainly exhibited dysrhythmia and the dominant frequency of EGG was normal. Some patients also exhibited non enhanced postprandial dominant power. The rate of GE among mild, moderate and severe symptom patients had no significant difference （P 〉 0.05 ）. The rate of abnormal EGG in severe symptom patients was significantly higher than that in mild and moderate symptom patients [92.9% （13/14） vs. 62.5% （10/16）, 66.7% （14/21）] （P 〈 0.05）. The rate of abnormal EGG in mild and moderate symptom patients had no significant difference （P 〉 0.05 ）. The rate of GE between Helicobacter pylori （Hp） positive patients and Hp negative patients had no significant difference （P 〉 0.05 ）. The rate of abnormal EGG in Hp positive patients was significantly higher than that in Hp negative patients [90.0% （18/20） vs. 61.3% （ 19/31 ） ] （P 〈 0.05 ）. The rate of GE and the rate of abnormal EGG had no significant difference between patients with and withoutactive gastritis（P 〉 0.05）. Conclusions The abnormality of EGG plays an important role in the pathogenesis of FD. There is no significant relationship between EGG and GE. The patients with severe symptom and with Hp positive have higher abnormal EGG percentage. Gastritis has no significant correlation with EGG or GE.

关 键 词：消化不良 胃排空 胃电图 

分 类 号：R57[医药卫生—消化系统]