锚状电极高温射频治疗肺转移瘤  

Percutaneous anchor-shaped electrode radiofrequency hyperthermia ablation of lung metastases

作　　者：赵正源[1] 程庆书[1] 王云杰[1] 刘锟[1] 李文海[1] 陈连宏[1] 王彩霞[1] 齐海妮[1] 

机构地区：[1]第四军医大学唐都医院胸外科,陕西西安710038

出　　处：《第四军医大学学报》2000年第11期1396-1398,共3页Journal of the Fourth Military Medical University

摘　　要：目的　对 CT引导下经皮肺穿刺锚状电极高温射频治疗肺转移瘤的临床效果和安全性进行研究 .方法　对 2 4例患者 16 1个不同病理类型的肺转移瘤进行锚状电极高温射频治疗 ,观察无创血压、脉搏和周围血氧饱和度的变化 ;治疗前后肺功能的变化 ;治疗后 CT扫描肿瘤组织中低密度影和肿瘤体积的变化 .结果　 2 4例患者治疗中血压、脉搏和周围血氧饱和度无明显改变 ;治疗后肺功能无明显改变 ;治疗后1wk内 CT扫描显示肿瘤体积均增大 ,治疗后 3m o肿瘤体积通过 CT扫描显示在 16 1个肿瘤中完全衰退 (CR) 2 3个(10 0 %衰退 ) ,部分衰退 (PRa) 98个 (80 %～ 10 0 %衰退 ) ,部分衰退 (PRb) 37个 (5 0 %～ 80 %衰退 ) ,无衰退 (NR) 3个 (衰退小于 5 0 % ) ;治疗后 3 mo CT扫描显示肿瘤内低密度影 型 3个 , 型 5 9个 , 型 99个 .结论　锚状电极高温射频治疗肺转移瘤效果良好并且创伤小 ,有良好的发展前景 .AIM To investigate the efficacy and safety of percutaneous anchor shaped electrode radiofrequency hyperthermia ablation guided by computerized tomography (CT) for the treatment of lung metastases. METHODS patients of lung metastases with 161 different pathological types were treated by radiofrequency technique. The patient's blood pressure, pulse rate and oxygen saturation were monitored during the procedure; the liver, pulmonary and renal functions were examined before and after the procedure. The tumor bulk and its low density shadow (LDS) were checked with CT after the treatment. RESULTS There were no changes in the blood pressure, pulse rate and oxygen saturation in the whole series before and after treatment, nor were the pulmonary functions either. The bulk of the tumor in this group as a whole was enlarged by the end of the first week after the therapy. The CT scanning of the tumor at the end of the third month revealed that there were 23 complete regression (CR) among 161 tumors, 98 partial regression with more than 80% decrease in tumor volume (PRa), 37 partial regression with 50%~80% decrease in tumor volume (PRb), and 3 no regression. The LDS of 161 tumors were checked by CT by the end of the third month showed 3 Ⅰtype (less than 50%), 59Ⅱ type (50%~80%) and 99 Ⅲ type (more than 80%). CONCLUSION Excellent clinical effects and safety of treatment for lung metastases with anchor shaped electrode radiofrequency hyperthermia ablation placed percutaneously by computerized tomography (CT) guided were recognized, and the trauma was recognized minimal, the well foreground was prognosticated.

关 键 词：锚状电极 射频消融术 肺转移瘤 高温射频 

分 类 号：R734.205[医药卫生—肿瘤] R730.59[医药卫生—临床医学]