CT引导经皮肺穿刺锚状电极高温射频消融治疗肺部肿瘤105例  

Percutaneous radiofrequency hyperthermia for lung cancer by the using of computer tomography-guided anchor-shaped electrode report of 105 cases

作　　者：程庆书[1] 赵正源[1] 刘锟[1] 王云杰[1] 王耀成[1] 李文海[1] 陈连宏[1] 齐海妮[1] 王彩霞[1] 

机构地区：[1]第四军医大学唐都医院胸外科,陕西西安710038

出　　处：《第四军医大学学报》2000年第11期1399-1401,共3页Journal of the Fourth Military Medical University

摘　　要：目的　观察 CT引导经皮肺穿刺高温射频消融治疗10 5例肺部恶性肿瘤的近期效果 .方法　 CT引导经皮肺穿刺 ,可扩展锚状电极配合 RF- 2 0 0 0仪高温射频消融治疗原发性肺癌 81例 ,肺部转移瘤 2 4例 ,共计 2 42个肿瘤 ,每个肿瘤治疗 3～ 8次 ,持续时间 3～ 337min.结果　完全缓解 (CR)率11.1% ,部分缓解 (PR)率 71.1% ,轻微疗效 (MR)率 13.2 % ,无改变 (NC)率 4.5 % ,其中 CR+ PR率为 82 .2 % .并发症包括气胸 34例、咯血 3例、少量血胸 4例、肺部感染 4例、心包填塞、应激性溃疡各 1例、局部疼痛 16例 .结论　 RF- 2 0 0 0型射频热疗机治疗肺部恶性肿瘤 ,近期疗效确切 ,严重并发症少 ,需严格掌握中心型肺癌的手术适应证 .AIM To explore the feasibility of clinical application of percutaneous radiofrequency hyperthermia (PRH) for lung cancer and its effect. METHODS 222 tumors of 81 patients with primary lung cancer and 24 metastases lung cancer were treated with PRH by the using of computer tomography guided anchor shaped electrodes (CTGASE). RESULTS Complete response of the tumor (CR) 11.1%, partial response (PR) 71.1%, minimal response (MR) 13.2%, no change (NC) 4.5%. The total of CR and PR (82.2%) indicated a satisfactory outcome. The complication of this procedure was minimal, including 34 cases of pneumothorax which were easily handled with aspiration, 3 cases of minimal hemoptysis and hemotharax for each, and 4 cases pneumonia, 1 cases of pericardial tamponade, 1 cases of hyperirritability ulcer. CONCLUSION PRH for lung cancer with CTGASE was proved to be a safe and effective procedure for inoperable lung cancer as well as for those who was not suitable for surgery during a short term observation up to date. This procedure should strictly by considered for central lung cancer.

关 键 词：肺肿瘤 CT引导 肺穿刺 锚状电极 高温射频消融 

分 类 号：R734.205[医药卫生—肿瘤] R730.59[医药卫生—临床医学]