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机构地区:[1]四川大学华西医院胃肠外科中心,成都610041
出 处:《中华胃肠外科杂志》2013年第10期933-936,共4页Chinese Journal of Gastrointestinal Surgery
基 金:国家自然科学基金(81071777);国家教育部新世纪优秀人才支持计划(2012SCU.NCET-11-0343);中央高校基本科研业务费专项资金--四川大学优秀青年学者科研基金(2011SCU04819)
摘 要:腹腔镜辅助远端胃癌根治术(LADG)是微创外科的技术之一,是现代外科的重要发展方向之一。按照日本胃癌治疗指南.LADG的适应证应严格限定在早期胃癌中,进展期胃癌应属于探索性临床研究。LADG在早期胃癌病例中应用的短期优势已得到较普遍地认可,但全腹腔镜技术尚需进一步研究探索;而LADG在进展期胃癌中的应用仍然是目前学术争议的热点之一。虽然当前有研究显示,LADG加D2淋巴结清扫对于进展期胃癌其效果与开腹手术相当,但仍需等待中国、日本和韩国目前正在进行的大样本多中心随机对照试验的结果确认。Laparoscopy-assisted distal gastrectomy (LADG) is a minimally invasive surgical technique, and also an important development of modern surgery. According to Japanese Gastric Cancer Treatment Guideline, indications of LADG must be strictly limited in early gastric cancer patients, while it should be investigated in advanced gastric cancer. Based on available studies, the short-tern1 advantage of LADG for eaHy gastric eancer has been generally accepted, but the totally laparoseopic technique for early gastric cancer is still tobe further studied. LADG for advanced gastric cancer eontinues to be controversial, which needs the relevant final results of randomized controlled trials from China, Japanese, and Korean to detennine, although some current studies have demonstrated similar efficacy of LADG plus D2 lymphadenectomy as compared to open gastrectomy.
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