难治性癫疒间MRI颞极信号特点与癫疒间的相关性分析  

Correlation analysis between the temporal pole signal abnormality on MRI and epilepsy in patients with intractable epilepsy

作　　者：陈述花[1,2] 王静[1,2] 史建国[3] 刘兴洲[1,2] 栾国明[1,2] 闫兆芬[1,2] 张玮[1,2] 李学秀[1,2] 

机构地区：[1]北京三博脑科医院 [2]首都医科大学第十一临床医学院神经外科,100093 [3]山东大学附属济南中心医院神经外科,济南250013

出　　处：《中国微侵袭神经外科杂志》2013年第10期446-449,共4页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨难治性癫疒间MRI颞极信号特点与致疒间区相关性。方法回顾性分析339例难治性癫疒间病人MRI颞极信号特点。根据癫疒间发作起始区将研究对象分为颞叶癫疒间、额叶癫疒间、顶叶癫疒间、枕叶癫疒间、岛叶癫疒间、多脑叶癫疒间等6类。结果颞极信号异常187例,颞极信号异常侧别与致疒间区侧别一致率达98.93%,颞极信号异常与癫疒间类型或致疒间区有关(χ2=311.339,P<0.001)。与颞叶外癫疒间比较,颞极信号异常更常见于颞叶癫疒间。结论在各类癫疒间中均可出现MRI颞极信号异常,但更常见于颞叶癫疒间。颞极信号异常侧常与致疒间区侧别一致,特别是颞叶癫疒间。Objective To study the relationship between the characteristics of the temporal pole signals on magnetic resonance imaging （MR/） and epileptogenic zone in intractable epilepsy. Methods The characteristics of the temporal pole signals of 339 patients with intractable epilepsy were analyzed retrospectively. Depending on the seizure onset zone, the patients were divided into 6 groups： temporal lobe, fIontal lobe, parietal lobe, occipital lobe, insular lobe and multiple lobe epilepsy. Results MR/demonstrated an abnormal signal in the temporal pole in 187 cases. There was a high consistence in the lateralization between the temporal pole MR/ abnormal signal and the seizure onset zone or epileptogenic zone, amounting to 98.93%. The temporal pole abnormal signal seemed to be correlated with epileptogenic zone （χ2= 311.339, P 〈 0.001）. The abnormal signal was more common in temporal lobe epilepsy than in extra-temporal lobe epilepsy. Conclusions The temporal pole abnormal MR/signal can be seen in all types of epilepsy and it showed high lateralization value in determination of the epileptogenic zone especially for temporal lobe epilepsy.

关 键 词：癫癎 难治性 颞极 磁共振成像 

分 类 号：R742.1[医药卫生—神经病学与精神病学]