微弧氧化处理纯钛种植体表面在模拟体液中可诱导磷灰石沉积  

Apatite-forming ability of pure titanium implant after micro-arc oxidation treatment

作　　者：田智慧[1] 张宇[1] 王立超[1] 南开辉[2] 

机构地区：[1]南方医科大学口腔医学院,南方医院口腔医院,广东广州510515 [2]华南理工大学材料学院,广东广州510641

出　　处：《南方医科大学学报》2013年第10期1554-1556,共3页Journal of Southern Medical University

基　　金：广东省科技计划项目(2007B010600051)

摘　　要：目的检测微弧氧化处理后的纯钛种植体表面体外矿化能力并且获得具有磷灰石涂层的种植体。方法将微弧氧化处理后获得的种植体浸泡在模拟生理溶液(SBF)液中,在不同时间点取出种植体,利用扫描电子显微镜(SEM)、X-射线衍射分析(XRD)、X-射线光电子能谱仪(XPS)分析其诱导磷灰石的能力和沉积物的形貌及组分。结果在SBF溶液中浸泡后,微弧氧化处理后的纯钛种植体表面有大量的钙磷盐沉积,微弧氧化样品在SBF中形成的矿化层以磷酸八钙(OCP)晶相为主,并含有一定量的碳酸羟基磷灰石(CHA)。结论经微弧氧化处理后的纯钛种植体可以在SBF中很好的诱导钙磷盐的沉积能力,其表面的矿化层主要由类似自然骨组织的低结晶度的CHA结晶层组成。Objective To investigate the apatite forming ability of pure titanium implant after micro-arc oxidation treatment in simulated body fluid （SBF） and obtain implants with calcium phosphate （Ca-P） layers. Methods The implants were immersed in （SBF） after micro-arc oxidation treatment for different time lengths, and their apatite forming ability and the morphology and constituents of the Ca-P layers formed on the sample surface were analyzed using X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy, and energy dispersive electron probe. Results After immersion in SBF, large quantities of Ca-P layers were induced on the surface of the samples. The Ca-P layers were composed of octacalcium phosphate and carbonated hydroxyapatite, and the crystals showed a plate-like morphology with an oriented growth. Conclusion The implants with micro-arc oxidation treatment show good apatite forming ability on the surface with rich calcium and phosphorus elements. The formed layers are composed of bone-like apatite including octacaldum phosphate and carbonated hydroxyapatite.

关 键 词：微弧氧化 钛种植体 生物活性表面 体外矿化 

分 类 号：R783[医药卫生—口腔医学]