HLA-A、B抗原分型与AIDP易感性  

Susceptibility of acute inflammatory demyelinating polyneuropathy(AIDP) and human leukocyte antigen(HLA) A,B antigens

作　　者：郭力[1] 林世和[2] 李春岩[1] 王维平[1] 刘瑞春[1] 王桂荣[1] 曹宁[1] 龚燕平[1] 

机构地区：[1]河北医科大学第二医院神经内科,河北石家庄050000 [2]白求恩医科大学一院神经内科,吉林长春130021

出　　处：《中风与神经疾病杂志》2000年第5期280-281,共2页Journal of Apoplexy and Nervous Diseases

摘　　要：目的　探讨 AIDP易感性与 HL A- A、B抗原分型的关联性。方法　对 31例 AIDP患者和 132例健康对照采用 PCR- SSP法进行 HL A- A、B抗原的基因分型。结果　 HL A - A 33抗原频率在 AIDP组升高 (P<0 .0 5 ) ,相对危险率 RR=6 .12 5。结论　 HL A- A33抗原与 AIDP易感性相关联。Objective To explore the association between susceptibility of AIDP and HLA A,B Antigen. Method HLA typing for A and B antigens was performed by PCR SSP on 31 patients with AIDP and 132 healthy cases as control group. Result The frequency of HLA A33 was increase in AIDP group (P<0.05). Conclusions HLA A33 antigen is associated with susceptibility of AIDP.

关 键 词：HLA分型 易感性 AIDP G-B综合征 

分 类 号：R745.430.2[医药卫生—神经病学与精神病学]