大豆磷脂对老龄大鼠单胺氧化酶、血小板、动脉内膜的影响  

EFFECTS OF SOYBEAN-PHOSPHOLIPIDS ON BRAIN MONOAMINE OXIDASE, PLATELETS AND ARTERIAL ENDOTHELIUM IN AGING RAT

作　　者：蔡惠罗[1] 李清焕[1] 刁凤英 甘雅玲[1] 卢宝廉[1] 

机构地区：[1]中国科学院动物研究所

出　　处：《动物学报》1991年第3期276-280,共5页ACTA ZOOLOGICA SINICA

摘　　要：本文观察了饲料添加剂大豆磷脂对老龄大鼠脑组织单胺氧化酶(MAO)活力、血小板聚集功能及主动脉内膜的影响。结果表示喂大豆磷脂24月龄大鼠组的大脑皮层、小脑、海马的MAO活力较对照组高,接近3月龄组;二磷酸腺苷(ADP)诱导血小板释放三磷酸腺苷(ATP)的量高于3月龄组,低于对照组;主动脉内膜扫描电镜观察内皮细胞轮廓清晰可见,有少数桥样结构,表面未见斑块样附着物,对照组则呈粥样硬化形态特征。上述结果提示,大豆磷脂作为饲料添加剂对某些衰老现象有明显的改善。Effects of soybean-phospholipid as dietary additive on brain monoamine oxidase activity, platelet function and arterial tunica intima in aging rat were studied. It was shown that brain MAO-A activity of the experimental group fed with soybean-phospholipid increased up to the level of the youth group, while MAO-B activity increased only slightly. Platelets of the experimental group released less ATP in response to ADP stimulation comparing with the control. Soybean-phospholipid also protected the aorta from atherosclerosis. These observations suggest that soybean-phospholipid may play a role in retardihg aging of the rats.

关 键 词：大鼠 大豆磷脂 单胺氧化酶 血小板 

分 类 号：Q959.837[生物学—动物学]