Notch及Wnt信号通路与子宫内膜癌  

Notch and Wnt signaling pathways with endometrial carcinorma

作　　者：孟丽荣[1] 郎斌[1] 

机构地区：[1]澳门理工学院高等卫生学校

出　　处：《现代肿瘤医学》2013年第10期2367-2369,共3页Journal of Modern Oncology

基　　金：澳门科学技术发展基金项目(028/2011/A2)

摘　　要：Notch信号通路是少数反复调节细胞增殖和凋亡的信号转导系统;Wnt信号通路是一个多环节、多作用位点的生长发育调控信号通路。二条通路的异常激活或结构性活化与子宫内膜癌的发生发展有关,本文就Notch及Wnt信号通路与子宫内膜癌发生发展的研究概况作一综述,为未来子宫内膜癌的治疗提供理论参考。The Notch signaling pathway responses as one of the minority system to regulate repeated celt promerauon and apoptotie signal transduction. The Wnt is a multi - link and multi - role signaling pathway for regulating growth and development. Abnormal activation or structural stimulation of these two pathways is related to the development of endometrial cancer. This review addresses present issues in the relationship between Notch, Wnt and endometrial cancer,which provides a theoretical reference to enhanceeurrent treatment.

关 键 词：NOTCH信号通路 WNT信号通路 子宫内膜癌 

分 类 号：R737.33[医药卫生—肿瘤]