不同浓度白酒对大鼠抗氧化酶活性的影响  

Effects of Different Doses of Liquor on Antioxidase Activity in Rats

作　　者：袁带秀[1] 申绪湘[2] 覃大保[1] 周琴[1] 

机构地区：[1]吉首大学医学院,湖南吉首416000 [2]吉首大学高教所,湖南吉首416000

出　　处：《酿酒科技》2013年第10期42-43,共2页Liquor-Making Science & Technology

基　　金：湘酒鬼股份有限公司科学研究计划项目<基于健康理念的馥郁香型酒鬼酒科学文化元素凝练及其运用研究>阶段性成果

摘　　要：研究不同浓度的白酒对大鼠血清和肝组织中SOD活力、T-AOC和MDA含量的影响。将40只雄性SD大鼠随机分成高浓度组(Ⅰ组)、中浓度组(Ⅱ组)、低浓度组(Ⅲ组)、对照组(Ⅳ组)。酒精灌胃建立动物模型,8周后测定血清和肝组织中SOD活力、T-AOC和MDA含量。结果表明,与对照组比较,高、中浓度白酒能使大鼠血清和肝组织中的SOD活力及T-AOC降低,MDA含量升高;低浓度白酒能使大鼠血清和肝组织中SOD活力及T-AOC升高,MDA含量降低;低浓度白酒对机体有一定的抗氧化和抗衰老作用;机体对酒的反应与用量有关,饮用少量对机体有积极作用。The effects of different doses of liquor on SOD activity,T-AOC and MDA content in rats serum and liver tissues were investigated. 40 healthy male SD rats were randomly divided into high alcohol group （ I group）, middle alcohol group （ II group）, low alcohol group （III group） and control group （IV group）. Rats model was then created by gastric feeding of liquor. After 8 weeks, the content of T-AOC and MDA and SOD activity in rats serum and liver tissues were detected. The results suggested that, compared with the control group, SOD activity and T-AOC con- tent reduced in high alcohol group and in middle alcohol group, and increased in low alcohol group, besides, MDA content increased in high alco- hol group and in middle alcohol group, and decreased in low alcohol group. Accordingly, low alcohol of liquor has certain antioxidant and an- ti-aging effects on the body, body reaction is closely related to drinking amount, and proper drinking is good for the health.

关 键 词：白酒 大鼠 超氧化物歧化酶 总抗氧化能力 丙二醛 

分 类 号：R285.5[医药卫生—中药学]