Bifunctional fluorescent probes for hydrogen peroxide and diols based on a 1,8-naphthalimide fluorophore  

作　　者：SUN Wei MA Zhao LI Jing LI WenHua DU LuPei LI MinYong 

机构地区：[1]Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmacy, Shandong University

出　　处：《Science China Chemistry》2013年第10期1440-1445,共6页中国科学（化学英文版）

基　　金：supported by the Shandong Natural Science Foundation(JQ201019);the Independent Innovation Foundation of Shandong University,IIFSDU(2010JQ005)

摘　　要：This report discloses a series of naphthalimide-based bifunctional fluorescent probes for hydrogen peroxide and diols.As a result,these molecules not only demonstrated high turn-on fluorescent response and good selectivity towards hydrogen peroxide over other relevant reactive oxygen species,but also displayed different responses to diols.Therefore,these fluorescent probes could be served as sensitive,selective and practical chemosensors for both hydrogen peroxide and diols under physiologicallike conditions.This report discloses a series of naphthalimide-based bifunctional fluorescent probes for hydrogen peroxide and diols. As a re- sult, these molecules not only demonstrated high turn-on fluorescent response and good selectivity towards hydrogen peroxide over other relevant reactive oxygen species, but also displayed different responses to diols. Therefore, these fluorescent probes could be served as sensitive, selective and practical chemosensors for both hydrogen peroxide and diols under physiological- like conditions.

关 键 词：1 8-NAPHTHALIMIDE bifunctional fluorescent probe hydrogen peroxide DIOLS 

分 类 号：R914[医药卫生—药物化学]