液基薄层细胞学在筛选非典型鳞状细胞阳性以上病变中的临床价值  

Clinical value of Thin-cytologic test in screening positive atypical squamous cells lesion

作　　者：陆勤燕[1] 周越球[1] 

机构地区：[1]空军杭州航空医学鉴定训练中心,310013

出　　处：《中国疗养医学》2013年第5期391-393,共3页Chinese Journal of Convalescent Medicine

摘　　要：目的回顾性分析83例采用液基薄层细胞学(TCT)法检测的非典型鳞状细胞(ASC)阳性以上病变,并经阴道镜检加病理组织学检测患者为阳性的相关资料,分析TCT技术在筛选ASC阳性以上病变中的临床价值。方法选择我院2009-01—2011-07就诊的经TCT检查结果为ASC阳性以上,并经阴道镜检加病理组织学检测为阳性的妇女83例,以阴道镜活检组织病理诊断为标准,TCT结果与病理组织学诊断进行对照。分析比较细胞学诊断为ASC阳性以上的病例经阴道镜诊断,阴道镜下活检与病理组织学诊断结果之间的关系。结果 ASC32例经阴道镜检病理组织学诊断CIN者为18例,诊断符合率为56%;30例LSIL经阴道镜检病理组织学诊断为CIN及以上者为24例,诊断符合率为80%;21例HSIL经阴道镜检病理组织学诊断为CIN者21例,诊断符合率为100%。TCT与阴道镜检病理组织学诊断符合率平均为79%。结论在TCT检测中ASC-US阳性以上的病例发生宫颈癌前病变率是较高的,运用高效合理规范化的筛查,能有效地降低宫颈癌的发病率和病死率。Objective To probe into the clinical value of TCT in screening ASC positive lesions with a retrospective analysis of 83 cases of using TCT to screen ASC positive lesions, and by colposcopy pathological detection in positive patients for relevant informa- tion.Methods 83 women in our hospital from 2009 January to 2011 July who were diagnosed with ASC positive by TCT and also positive by colposcopy and pathological detection were treated with the standard of colposcopy biopsy hisopathology diagnosis, TCT re- suits in contrast with histodiagnosis.The relation between the diagnosis of ASC positive by colposcopy,Analysis and comparison of cy- tology in the diagnosis of ASC positive over the case by colposcopy, colposcoped biopsy and pathologic histology was analyzed. Results 18 out of 32 patients with ASC by colposcopy pathological detection were diagnosed with C1N,the diagnostic accordance rate was 56% ; 24 out of 30 patients with LSIL by colposcopy pathological detection were diagnosed with C1N, the diagnostic accordance rate was 80%;21 out of 21 patients with HSIL by colposcopy pathological detection were diagnosed with C1N, the diagnosis accordance rate was 100%o.The average diagnosis accordance rate of TCT and colposcopy pathological detection was 79%o.Conclusion There is a high rate of precancerous lesions of uterine cervix among ASC-US positive in TCT screening, and through efficient and normalized screen- ing, the incidence and case fatality rate of cervical cancer can be effectively reduced.

关 键 词：液基薄层细胞学 宫颈癌 宫颈上皮内瘤变 

分 类 号：R737.33[医药卫生—肿瘤]