酒精性肝纤维化中医证型与肝纤4项、影像学及病理分期相关性研究  

Study on the relationship between syndrome classification and serology indexes,radiology and pathological stage of Alcoholic Liver Fibrosis( ALF)

作　　者：陈润花[1] 陈亮[2] 师宁[2] 刘敏[3] 孙建光[4] 王宪波[5] 金贤国 丁霞[7] 

机构地区：[1]北京中医药大学东方医院脾胃肝胆科,北京100078 [2]北京中医药大学东直门医院消化科,北京100700 [3]首都医科大学附属北京市中医医院肝病科,北京100010 [4]山东中医药大学附属医院肝病科,济南250011 [5]首都医科大学附属地坛医院中西医结合中心,北京100015 [6]吉林省延吉市中医医院消化科,吉林延吉133000 [7]北京中医药大学研究生院,北京100029

出　　处：《中国中医基础医学杂志》2013年第10期1202-1204,共3页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：国家"十一五"科技支撑计划(2006BAI08B01-07);国家自然科学基金资助项目(91129714)

摘　　要：目的:探讨酒精性肝纤维化的理化指标在中医证型辨识中的价值。方法:探讨326例酒精性肝纤维化患者的中医证型与肝纤4项、影像学(肝大、脾大、门静脉增宽)和病理分期之间的关系。结果:各项理化指标均与中医证型之间存在相关性(P<0.05),影像学与气滞血瘀证关系最密切;湿热蕴结证和气滞血瘀证贯穿整个病理分期;肝纤4项与中医证型存在相关性。结论:肝纤4项、影像学、病理分期等理化指标与中医证型之间存在相关性。Objective： To investigate the objectivity of syndrome classification of Alcoholic Liver Fibrosis （ALF）. Methods ： The relationship between syndrome patterns of 326 confirmed ALF patients and four indicators of hepatic fibrosis, radiology （hepatomegaly, splenomegaly, portal vein enlargement） and pathological stage was analyzed. Results： The physical and chemical indexes were all correlated with syndrome patterns （ P 〈 0.05 ） , radiology was more closely with Qi stagnation and blood stasis. Accumulation of dampness and heat, Qi stagnation and blood stasis lasted the whole process of pathological changes. Each of Four indicators of hepatic fibrosis was closely related with syndrome patterns. Conclusion： There was a clear correlation between syndrome patterns and four indicators of hepatic fibrosis, radiology and pathological stage.

关 键 词：酒精性肝纤维化 证候 理化指标 

分 类 号：R575.5[医药卫生—消化系统]