儿童消化性溃疡小肠细菌过度生长情况研究  

A Study on small intestinal bacterial overgrowth in children peptic ulcer

作　　者：王为[1] 冷明芳[1] 韩龙[1] 雷丝丝[1] 葛妍芹[1] 蔡娜[1] 

机构地区：[1]解放军第169医院消化内科,湖南衡阳421002

出　　处：《临床军医杂志》2013年第10期1013-1014,共2页Clinical Journal of Medical Officers

摘　　要：目的探讨儿童消化性溃疡(PU)患者小肠细菌过度生长(SIBO)的情况,以及SIBO与其幽门螺杆菌(HP)感染之间的关系。方法对30例儿童PU患者按HP感染情况分为HP阳性组(22例)、HP阴性组(8例)两组,通过葡萄糖氢呼吸试验(GHBT)分别检测其SIBO情况,并与健康对照组进行组间比较。结果 30例儿童PU患者,HP阳性组和HP阴性组患儿与健康对照组的SIBO阳性率及试餐后呼气氢浓度比较差异均有统计学意义(P<0.01);儿童PU患者HP阳性组与HP阴性组SIBO阳性率及试餐后呼气氢浓度比较差异也有显著统计学意义(P<0.01)。结论儿童消化性溃疡SIBO发生率高,若合并HP感染,其SIBO发生率增加尤为显著,推测儿童消化性溃疡SIBO阳性率高与幽门螺杆菌存在某种关联。Objective To investigate the conditions of small intestinal bacterial overgrowth （ SIBO ） in children with peptic ulcer （ PU）, as well as its correlation with helicobaeter pylori （HP） infection. Methods Thirty children with PU were divided into HP positive group （n = 22） and negative group （n = 8）. Their SIBO were detected by glucose hydrogen breath test （GHBT） and com- pared with that of healthy control group. Results There were significant differences in positive rate of SIBO and in breath hydrogen concentration after a meal between any of the two child groups and the control group （P 〈 0. 01 ）. Between the two child groups, there were also significant differences in the above parameters （ P 〈 0.01 ）. Conclusion In the children with PU, the incidence of SIBO is high. In addition to HP infection, it increases significantly. We speculate that there is a certain relationship between high positive rate of SIBO and HP in children with PU.

关 键 词：消化性溃疡 儿童 幽门螺杆菌 小肠细菌过度生长 葡萄糖氢呼气试验 

分 类 号：R573.1[医药卫生—消化系统]