血清鳞状细胞癌抗原与鼻咽癌的关系研究  

Relationship between serum squamous cell carcinoma antigen and nasopharyngeal carcinoma

作　　者：黄玲莎[1] 江宗蔚[1] 李美琴[1] 朱波[1] 黄文成[1] 陈艳华[1] 

机构地区：[1]广西医科大学附属肿瘤医院检验科,南宁530021

出　　处：《检验医学与临床》2013年第20期2652-2652,2654,共2页Laboratory Medicine and Clinic

基　　金：广西壮族自治区卫生厅立项项目(Z2010149)

摘　　要：目的探讨血清鳞状细胞癌相关抗原(SCCAg)在鼻咽癌人群的表达及其与鼻咽癌发生远端转移的关系。方法根据TNM分期有无发生远端转移分为M1、M0组。采用酶联免疫检测法,检测鼻咽癌患者M0组90例,M1组33例血清中的SCCAg表达水平。结果鼻咽癌M0组SCCAg阳性率为5.56%,M1组SCCAg阳性率为27.27%,两组比较差异有统计学意义(P<0.05)。结论 SCCAg作为鼻咽癌的筛查指标敏感度偏低,而对鼻咽癌是否发生远端转移有一定的临床意义。Objective To investigate the correlation between squamous cell carcinoma antigen （SCCAg） with distant metastasis of nasopharyngeal carcinoma （NPC） .Methods NPC patients were divided into M0 group for 90 cases and M1 group for 33 cases ,according to TNM staging and distant metastasis ,and detected for serum SCCAg level .Results The positive rates of SCCAg in M0 and M1 group were 5 .56% and 27 .27% ,with statistical difference between the two groups （P〈0 .05） .Conclusion SCCAg might be not sensitive for the screening of NPC ,but could be with clinical significance for the diagnosis of distant metastasis .

关 键 词：鳞状细胞癌相关抗原 鼻咽癌 远端转移 

分 类 号：R737.33[医药卫生—肿瘤]