热带地区宫颈癌TCT筛查结果分析  

Characteristics of TCT cervical cancer screening in tropical area.

作　　者：陈运春[1] 林丽英[1] 郑春娇[1] 曹晓强[1] 

机构地区：[1]海南省农垦总医院检验科,海口570311

出　　处：《诊断病理学杂志》2013年第10期642-645,共4页Chinese Journal of Diagnostic Pathology

摘　　要：目的分析液基薄层细胞学检测（TCT）筛查热带地区宫颈癌的病变特征,探讨TCT在宫颈癌筛查中的价值。方法采用TCT检测12 231例宫颈细胞标本,根据TBS系统做出判读,并对结果进行回顾性分析。结果12 231例宫颈细胞标本中,细胞学阳性检出率从≥16岁组到≥80岁组,呈逐渐上升趋势（χ2=12.99,P〈0.05）。活检确诊宫颈癌6例（鳞状细胞癌5例,腺癌1例）,占0.05%（6/12 231）,平均年龄58.50±9.33岁;CIN2~3占0.33%（40/12231）,平均年龄41.35±8.95岁;CIN1占0.21%（26/12 231）,平均年龄39.77±9.57岁。结论热带地区宫颈癌筛查呈现出低检出率和癌症发病高龄化的情况,因此,进行宫颈癌TCT筛查工作时要考虑不同的地区、不同人群的情况,适当延长热带地区筛查的终止年龄。Objective To investigate the cervical cancer TCT （liquid-based thin-layer cytology） screening characteristics and significance in tropical region. Methods 12231 cervical samples were detected by TCT from Jan. 2011 to Oct. 2012, and then diagnosis was made according to TBS, and the results were analyzed retrospectively. Results Among 12231 cervical specimens, the positive rate of cytology results increased gradually from 16- years old group to 80- year old age group （X2 = 12. 99, P 〈 0. 05 ）. Biopsy examination showed that 6 cases of cervical cancer （ 5 cases of squamous cell carcinoma and 1 case of ad ） accounted for 0.05% （6/12231）, with an average age of 58. 5 ± 9. 33 years CIN2 -3 accounted for 0. 33% （40/12231）, with an average age of 41.35 ±8.95 and CIN1 accounted for 0. 21% （26/ 12231 ） with an average age of 39. 77 ± 9. 57. Conclusion Tropical cervical cancer screening presents a low detection rate and the higher cancer risk in older groups. It is suggested that the duration of TCT screening should be prolonged in the tropical region.

关 键 词：热带 液基细胞学 宫颈癌 筛查 检出率 

分 类 号：R737.33[医药卫生—肿瘤]