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作 者:单国平[1] 戎亚雄[1] 姜丹乾[1] 朱大刚[1] 张良良[1] 蒋继文[1]
机构地区:[1]江苏大学附属武进医院普通外科,江苏常州213002
出 处:《中国普通外科杂志》2013年第10期1271-1275,共5页China Journal of General Surgery
摘 要:目的:探讨T4胃癌根治切除术患者的生存情况及预后影响因素。方法:对2007年1月—2011年12月收治的有完整临床及随访资料的183例T4胃癌根治切除术患者行回顾性分析。结果:全组患者1,3,5年累积生存率分别为92%,60%,42%,单因素分析显示,淋巴结转移率、pN分期、肿瘤浸润深度、组织学类型与患者术后生存率有关(均P<0.05);多因素分析显示,淋巴结转移率、pN分期、肿瘤浸润深度是影响患者预后的独立危险因素(均P<0.05)。结论:淋巴结转移率、pN分期、肿瘤浸润深度是影响T4胃癌根治切除术患者生存的独立预后因素。Objective: To analyze the survival and prognostic factors in T4 gastric cancer patients after radical resection. Methods: Retrospective analysis was conducted in 183 T4 gastric cancer patients with complete clinical and follow-up data, who underwent radical resection from January 2007 to December 2011. Results: In the entire group of patients, the 1-, 3- and 5-year cumulative survival rate was 92%, 60% and 42%, respectively. Univariate analysis showed that the metastatic lymph node ratio, pN stage, depth of invasion and histological type were significantly associated with the survival of the patients (all P〈0.05). Multivariate analysis revealed that the metastatic lymph node ratio, pN stage, and depth of invasion were the independent risk factors for the prognosis of the patients (all P〈0.05). Conclusion: Metastatic lymph node ratio, pN stage and depth of invasion are important factors postoperative survival ofT4 gastric cancer patients undergoing radical resection. affecting the
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