糖尿病对大脑中动脉闭塞患者软脑膜侧支循环建立的影响  

Effect of diabetes mellitus on establishing the leptomeningeal collateral circulation in patients with middle cerebral artery occlusion

作　　者：郭芳[1] 谢琰臣[1] 张拥波[1] 李继梅[1] 

机构地区：[1]首都医科大学附属北京友谊医院神经内科,100050

出　　处：《临床神经病学杂志》2013年第5期332-334,共3页Journal of Clinical Neurology

摘　　要：目的探讨糖尿病对大脑中动脉闭塞患者软脑膜侧支循环建立的影响。方法对101例动脉粥样硬化所致的大脑中动脉近端（M．、M：段）闭塞患者进行头颅CT血管成像检查以评估软脑膜侧支循环建立等级。对伴和不伴糖尿病病史的患者软脑膜侧支循环建立等级进行比较分析。结果本组中软脑膜侧支循环建立等级为1～2级者62例（61．4％），3—5级者39例（38．6％）。伴糖尿病的大脑中动脉闭塞患者软脑膜侧支循环建立等级在1—2级的比例与无糖尿病者比较，差异无统计学意义（P：0．546）。糖尿病病史〈10年的患者软脑膜侧支循环建立等级在1—2级的比例与糖尿病病史≥10年者比较，差异无统计学意义（P=0．222）。糖化血清蛋白增高的患者软脑膜侧支循环建立等级在1～2级的比例与糖化血清蛋白正常者比较，差异无统计学意义（P=0．844）。结论糖尿病与大脑中动脉近端闭塞患者的软脑膜侧支循环建立等级无关。Objective To investigate the effect of diabetes mellitus （DM） on establishing the leptomeningeal collateral circulation in patients with middle cerebral artery occlusion （MCAO）. Methods The cerebral arteries image by CT were completed on 101 patients with atherosclerotic MCAO （ M1, M2 stage） to assess the grades of leptomeningeal collateral circulation. The grades of leptomeningeal collateral circulation between patients with and without DM were compared. Results The were 62 eases （ 61.4% ） with 1 - 2 gread of leptomeningeal collateral circulation in this group, and 39 cases （38.6%） with 3 -5 gread. The difference of the rate of 1 -2 gread between patients with and without DM was no statistical significance （ P = 0. 546 ）. The difference of the rate of 1 - 2 gread between patients with DM 〈 10 years and with DM I〉 10 years was no statistical significance （ P = 0. 222 ）. The difference of the rate of 1 - 2 gread between patients with high glycosylated serum protein and with normal glycosylated serum protein was no statistical significance （P = 0. 844 ）. Conclusion DM is not related with the grades of leptomeningeal collateral circulation in patients with MCAO.

关 键 词：糖尿病 大脑中动脉闭塞 侧支循环 

分 类 号：R743.3[医药卫生—神经病学与精神病学]