阿维菌素类药物毒理学研究进展  

Research Advances of Avermectins Toxicology

作　　者：李铭[1] 冯伟[1] 崔玉 袁改霞[1] 徐长君[1] 殷亚杰[1] 聂春雨[1] 

机构地区：[1]大庆师范学院生命科学学院,黑龙江大庆163712 [2]齐齐哈尔市梅里斯区第二中学,黑龙江齐齐哈尔161021

出　　处：《安徽农学通报》2013年第20期29-32,39,共5页Anhui Agricultural Science Bulletin

基　　金：黑龙江省教育厅科学技术研究项目(12513003)

摘　　要：阿维菌素是一种高效、低毒、安全的驱虫药,属十六元大环内酯类化合物,在市场上占有较大的销售份额。其在农畜业生产中发挥重要作用的同时也对生态环境造成越来越严重的威胁。虽然阿维菌素类药物对多种生物类群均有毒副作用,但从已发布的研究结果来看,水生生物对该类制剂最为敏感,因此仅就阿维菌素对水生生物的毒理学研究进展作一综述。As an efficient, low toxicity and safe anthelmintic,avermectins （AVMs） are belonging to the sixteen membered macrolide compound and take a large share of sales in the market. They play an important role in agricuhure and animal husbandry production. At the same time,they cause more and more serious threat to the ecological environment. Although avermectins can produce toxic side effects to a variety of biological taxa,aquatic organisms are most sensitive to these pesticides according to the research results published. In this article,the toxicology studies about avermectins to aquatic organisms were reviewed.

关 键 词：阿维菌素 作用机理 毒性 中毒症状 

分 类 号：R151.3[医药卫生—营养与食品卫生学]