Epi-LASIK和LASIK治疗近视散光的早期疗效对比观察  

Comparative study of Epi- LASIK and LASIK for myopic astigmatism

作　　者：罗栋强[1] 王华[1] 何书喜[1] 陈蛟[1] 

机构地区：[1]湖南省人民医院眼视光中心,中国湖南省长沙市410002

出　　处：《国际眼科杂志》2013年第11期2290-2292,共3页International Eye Science

摘　　要：目的:探讨分析角膜微型刀上皮瓣下准分子激光原位角膜磨镶术(epipolis laser in situ keratomileusis,Epi-LASIK)和准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)治疗近视散光的疗效。方法:近视散光行Epi-LASIK治疗的患者32例64眼,LASIK治疗的患者63例126眼,将患者根据柱镜度数分为2组:Ⅰ组(柱镜-0.25～-2.75D,Epi-LASIK 20例、LASIK 48例)、Ⅱ组(柱镜-3.00～-5.00D,Epi-LASIK 12例、LASIK 15例)。随访6mo观察两种术式的疗效。对比两组患者的术后裸眼视力(uncorrected visual acuity,UCVA)、最佳矫正视力(best corrected visual acuity,BCVA)、残余散光度、角膜愈合情况、眼压及角膜地形图等。结果:术后6mo,Ⅱ组中UCVA较术前明显提高,EpiLASIK为21眼(87.5%),LASIK为19眼(63.3%),两术式相比较差异有显著性(χ2=4.055,P<0.05);残余散光度Epi-LASIK为-0.41±0.30D,LASIK为-0.74±0.36D,两术式相比较差异有显著性(t=2.672,P<0.05);角膜散光Epi-LASIK为0.63±0.34D,LASIK为0.81±0.52D,两术式相比较差异有显著性(t=2.234,P<0.05)。结论:Epi-LASIK治疗≥-3.00D散光与LASIK相比具有更好的效果和预测性。AIM： To analyze the effects of epipolis laser in situ keratomileusis （ Epi - LASlK ~） and laser in situ keratomileusis （ LASIK ~） for treatment of myopic astigmatism. ~ METHODS： For treatment of myopic astigmatism, 32 patients （64 eyes） treated by Epi-LASIK and 63 patients （126 eyes） received LASlK. By their degree of astigmatism, the eyes were divided into Group I （-0.25 ~ -2.75） DC and Group II （-3.0^-5.0）DC. During the6-month follow- up, the early effects of the two operations were observed and compared in terms of uncorrected visual acuity （UCVA）, best corrected visual acuity （ BCVA）, residual astigmatism, corneal healing, intraocular pressure （lOP）, corneal topography. ~ RESULTS： In Group II , UCVA better than 20/20 was achieved in 87.5% of the eyes subjected to Epi-LASlK and in 63.3% of the eyes subjected to LASlK, with significant difference between them （X2 = 4. 055, P〈0.05） ; residual astigmatism was -0.41 ＋0.30D for the Epi-LASlK eyes and -0. 74 _＋ 0. 36D for the LASlK eyes, with significant difference between them （t = 2. 672, P 〈 0. 05 ）; postoperative corneal astigmatism was 0.63＋0.34D for the Epi-LASIK eyes and 0.81 _＋0.52D for the LASlK eyes with significant difference between them （ t= 2. 234, P〈0.05）. ~ CONCLUSION： For treatment of high astigmatism （ i〉-3.00D） , Epi-LASIK is more effective and predictive than LASIK.

关 键 词：角膜微型刀上皮瓣下准分子激光原位角膜磨镶术 准分子激光原位角膜磨镶术 散光 

分 类 号：R779.63[医药卫生—眼科]