副肿瘤性边缘叶脑炎的临床及影像学特征  

Clinical and magnetic resonance imaging characteristic

作　　者：汪东[1] 王伟光[1] 宁铁英[1] 吕少萍[2] 

机构地区：[1]青岛大学医学院第二附属医院,山东青岛266042 [2]山东大学附属省立医院,山东济南250021

出　　处：《泰山医学院学报》2013年第8期605-607,共3页Journal of Taishan Medical College

基　　金：山东省医药卫生科技发展计划项目(2005JZ003)

摘　　要：目的探讨副肿瘤性边缘叶脑炎(paraneoplastic limbic encephalitis,PLE)的临床及影像学特征。方法采用回顾性分析方法,分析PLE患者的临床、神经电生理及影像学特征。结果病人主要表现记忆力及定向力等高级智能障碍、癫痫发作、精神障碍等,脑脊液检查呈炎性改变(脑脊液蛋白72 mg/dl,细胞数75个/mm3),脑MRI提示右颞叶异常信号改变,脑电图示右侧颞叶慢波等。结论脑脊液、脑MRI及神经电生理检查有助早期明确PLE诊断。Objective： To investigate the clinical and magnetic resonance imaging characteristics. Methods： The clinical, neuro-electrephysiology and neuroimaging features in one case diagnosed PLE were analysed. Results： The main manifestations were cognitive dysfunction, seizures and psychiatric symptoms. Cerebrospinal fluid examination indicated a modest elevation of protein （75mg/dl） and a mild elevation of CSF pleocytosis （75 cells/ram3）. Cranial MRI showed increased T2 wighted in the right temporal lobe, and EEG showed the slow wave in the right temporal lobe. Conclusion： Cerebrospinal fluid, cranial MRI and EEG can contribute to the early diagnosis of PLE.

关 键 词：副肿瘤性边缘叶脑炎 临床特征 影像学 

分 类 号：R734.2[医药卫生—肿瘤]