内质网应激/未折叠蛋白反应与非酒精性脂肪性肝病  

Endoplasmic Reticulum Stress/unfolded Protein Response and Non-alcoholic Fatty Liver Disease

作　　者：王涛[1] 陈东风[1] 

机构地区：[1]第三军医大学大坪医院野战外科究所消化内科,重庆400042

出　　处：《现代生物医学进展》2013年第26期5168-5172,共5页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81170382)

摘　　要：近年来,由于内质网应激/未折叠蛋白反应可影响物质代谢途径中的许多环节,故在非酒精性脂肪性肝病中起的作用越来越受到重视。现就内质网应激/未折叠蛋白反应在非酒精性脂肪性肝病中的作用和影响作一综述。Recently, the roles of endoplasmic reticulum stress/unfolded protein response in NAFLD are more and more important because of their effects on some component elements of metabolism pathway. Herein we review the effects of endoplasmic reticulum stress/unfolded protein response in NAFLD.

关 键 词：内质网应激 未折叠蛋白反应 非酒精性脂肪性肝病 

分 类 号：R575.5[医药卫生—消化系统]