中分化松果体实质肿瘤(附6例报告)  

Pineal parenchymal tumors of intermediate differentiation: a report of six cases

作　　者：黄冠又 张岩[2] 汤劼[2] 吴震[2] 张力伟[2] 张俊廷[2] 

机构地区：[1]贵阳市第二人民医院神经外科,贵州贵阳550081 [2]首都医科大学附属北京天坛医院神经外科,北京100050

出　　处：《国际神经病学神经外科学杂志》2013年第4期317-320,共4页Journal of International Neurology and Neurosurgery

基　　金：卫生行业科研专项基金(编号:200902004);首都医学科研发展基金(编号:2009-1040)

摘　　要：目的总结中分化松果体实质肿瘤的临床特点和治疗。方法回顾性分析6例中分化松果体实质肿瘤病人的临床资料,3例行Poppen入路,2例行胼胝体穹隆间入路,1例经侧脑室三角区入路。术后4例患者放疗,2例行化疗。结果肿瘤全切除1例,次全切除4例,部分切除1例。术后围手术期死亡1例,随访5例患者,死亡1例,余4例存活。结论中分化松果体实质肿瘤比较罕见,诊断主要依靠临床表现、影像学及组织病理特征。治疗首先手术联合术后辅助放疗、化疗。Objective To summarize the clinical features and treatment of pineal parenchymal tumors of intermediate differentiation（PPTIDs）.Methods A retrospective analysis was performed on the clinical data of 6 patients with PPTIDs.Poppen approach was used in 3 cases,transcallosal interforniceal approach was used in 2 cases,and transtrigone lateral ventricle approach was used in 1 case.After operation,4 patients received radiotherapy,and 2 patients received chemotherapy.Results All the tumors were surgically removed,including total resection in 1 case,subtotal resection in 4 cases,and partial resection in 1 case.After operation,1 patient died during the perioperative period;among 5 patients followed up,1 died,and 4 survived.Conclusions PPTIDs are rarely seen.The diagnosis of PPTIDs mainly depends on clinical manifestations,radiological findings,and histopathological features.The patients with PPTIDs should be treated by microsurgery combined with postoperative radiotherapy and chemotherapy.

关 键 词：中分化松果体实质肿瘤 组织学 分子遗传学 

分 类 号：R739.4[医药卫生—肿瘤]