长春西汀联合醒脑静治疗急性脑梗死的疗效观察  

Curative effect of vinpocetine combined with Xingnaojing in treating acute cerebral infarction

作　　者：姚东陂[1] 王红欣[2] 陶小伟[1] 李玲[1] 张锦丽[1] 

机构地区：[1]北京军区总医院二六三临床部神经内科,北京101149 [2]北京军区总医院二六三临床部放射科,北京101149

出　　处：《北京医学》2013年第11期907-909,共3页Beijing Medical Journal

摘　　要：目的观察长春西汀联合醒脑静治疗急性脑梗死的临床疗效。方法将急性脑梗死患者60例随机分为对照组和治疗组,每组30例,对照组给予注射用血栓通治疗,治疗组给予长春西汀联合醒脑静静脉滴注治疗,两组疗程均为14 d。比较两组治疗前后神经功能缺损评分(National Institutes of Health Stroke Scale,NIHSS)改善状况及临床疗效。结果治疗组治疗前后NIHSS评分分别为12.48±3.48和6.14±3.07,对照组分别为12.72±4.03和8.32±3.61,治疗组改善状况优于对照组,差异有统计学意义(P<0.05);治疗组总有效率为86.7%,优于对照组的63.3%,其差异有统计学意义(P<0.05)。结论长春西汀联合醒脑静治疗急性脑梗死安全有效。Objective To observe the clinical curative effect of vinpocetine combined with Xingnaojing in treating acute cerebral infarction.Methods Sixty acute cerebral infarction patients were randomly assigned to the control group and treatment group with 30 cases in each.The control group was given Xueshuantong injection for treatment,while the treatment group was given vinpocetine combined with Xingnaojing.The two groups were treated for 14 d.The neural function defect score （National Institutes of Health Stroke Scale,NIHSS） before and after treatment were compared before and after treatment.Results NIHSS score of the treatment group changed from 12.48±3.48 to 6.14±3.07,while the NIHSS score of the control group changed from 12.72±4.03 to 8.32±3.61,the improvement of the treatment group was more significant than the control group.The difference was statistically significant （P ＜ 0.05）.The total effective rate of the treatment group was 86.7％,while the total effective rate of the control group was 63.3％,the difference was statistically significant （P ＜ 0.05）.Conclusion Vinpocetine combined with Xingnaojing in treating acute cerebral infarction is safe and effective.

关 键 词：急性脑梗死 长春西汀 醒脑静 临床疗效 

分 类 号：R743.33[医药卫生—神经病学与精神病学]