他汀类药物对脑梗死患者血脂及C反应蛋白的影响  

The impact of Statins on serum level of C-reactive protein in patients with cerebral infarction

作　　者：张凤莹[1] 刘艳文[1] 张晓蕾[1] 李前文[2] 

机构地区：[1]江苏淮阴卫生高等职业技术学校基础部,淮阴2230002 [2]中国人民解放军第82医院,淮安223000

出　　处：《中国实用神经疾病杂志》2013年第19期26-27,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨他汀类药物对脑梗死患者C反应蛋白的影响。方法选取2011-01—2012-01我院收治的60例脑梗死患者,在血小板抑制剂、脑保护剂和改善脑循环药物基础上,加用辛伐他汀15mg/d治疗。检查治疗前后CRP、TC、TG、HDL-C、LDL-C、AST、CK水平。结果 60例患者治疗后TC、TG、HDL-C、CRP水平均明显下降。结论他汀类药物对脑梗死患者CRP水平有明显影响,并且他汀类药物在临床观察期间无不良反应,安全性较好。Objective To investigate the impact of Statins on serum level of C-reactive protein in patients with cerebral in- farction. Methods Totally 60 patients with cerebral infarction into our hospital from January 2011 to January 2012 were includ- ed. These 60 patients received platelet inhibitors, neuroprotective agents and cerebral circulation improving drugs on the basis of ADD simvastatin 15 mg/d treatment. Before and after clinical treatment, serum levels of CRP, TC, TG, HDL-C, LDL-C, AST, CK levels were detected. Results The serum level of TC, TG, HDL-C and CRP in all 60 patients in the clinical treat- ment decreased significantly. Conclusion Statins may have a significant effect on serum level of CRP in patients with cerebral infarction, and have no adverse reactions, and with better safety.

关 键 词：他汀类药物 脑梗死 C反应蛋白 

分 类 号：R743.33[医药卫生—神经病学与精神病学]