高压氧联合神经节苷酯辅助治疗高血压脑出血术后效果分析  

Clinical efficacy of hyperbaric oxygen combined with ganglioside on post-operative hypertensive intracranial hemorrhage

作　　者：王宏盛[1] 陈正楼[1] 胥敏[1] 季宏建[1] 

机构地区：[1]江苏盐城市第三人民医院南院神经外科,盐城224001

出　　处：《中国实用神经疾病杂志》2013年第20期25-26,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨高压氧与神经节苷酯辅助治疗幕上高血压脑出血的临床治疗效果。方法将我院2004-01-2011-12收治的150例高血压脑出血患者随机分为3组,A组50例患者给予高压氧配合显微手术治疗,B组50例给予神经节苷脂配合显微手术治疗,C组50例给予高压氧与神经节苷脂辅助显微手术治疗,观察3组临床治疗效果。结果 A组总有效率72.0%,B组74.0%,C组90.0%。C组总有效率明显的高于A组和B组,差异有统计学意义(P<0.05);A组和B组临床治疗总有效率比较差异无统计学意义(P>0.05);3组治疗后神经功能缺损评分较治疗前有明显改善,C组改善程度明显高于A组和B组,差异有统计学意义(P<0.05)。结论临床中对于高血压脑出血患者给予高压氧与神经节苷脂辅助显微手术清除血肿治疗效果显著,可有效改善患者神经功能。Objective To investigate the effects of hyperbaric oxygen combined with ganglioside complementary therapy after microsurgery on the hypertensive intracerebral hemorrhage. Methods From February 2004 to December 2011 in our hos- pital 150 cases of hypertensive cerebral hemorrhage after microsurgery were randomly were divided into three groups, 50 cases in group A were treated with hyperbaric, 50 cases in group B were treated with ganglioside treatment, 50 cases in group C were treated with hyperbaric oxygen combined with ganglioside, and the efficacy of the three groups was analyzed. Results The total effective rate in group A was 72%, which was 74% and 90% in group B and group C respectively. Compared with group A and B, clinical efficacy in group C was significantly improved （P〈 0.05） ; Compared with group A, group B, the neurological deficit scores of group C,was improved significantly, the difference was statistically significant（P〈 0.05）. Conclusion After microsurgery, inhalation of hyperbaric oxygen combined with ganglioside may be a safe and effective method for hypertensive cerebral hemorrhage patients.

关 键 词：高血压脑出血 高压氧 神经节苷脂 临床疗效 

分 类 号：R743.34[医药卫生—神经病学与精神病学]