胼胝体前部胶质瘤的临床特点及应用显微手术切除的可行性  

Clinical features and the feasibility of application of microsurgical resection of the corpus callosum front of the glioma

作　　者：朱江[1] 

机构地区：[1]四川省肿瘤医院神经外科,成都610041

出　　处：《中国实用神经疾病杂志》2013年第20期26-28,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的分析胼胝体前部胶质瘤患者的病理学特征以及应用显微手术治疗的安全性及预后效果。方法选取本院2008-01—2010-12收治的胼胝体前部胶质瘤患者26例为研究对象,回顾性分析患者的临床资料。随机将患者分为显微手术切除治疗组(观察组)13例以及传统手术治疗组(对照组)13例,对比分析两种治疗方法的治疗效果,术后对患者进行评价。结果胼胝体前部胶质瘤患者临床主要表现为颅内高压、认知功能障碍、癫疒间等症状。经影像学诊断,8例病变局限于胼胝体内,11例出现侵犯额叶,3例病灶侵犯侧脑室壁,2例侵犯边缘系统脑组织,2例侵犯顶叶。观察组患者术中出血量、平均手术时间、平均住院时间显著优于对照组,差异有统计学意义(P<0.05)。高级别胶质瘤患者显著多于低级别胶质瘤患者,差异有统计学意义(P<0.05)。结论对胼胝体前部胶质瘤患者应用显微手术切除肿瘤可有效减少术中出血量,缩短患者住院时间,提高患者生存质量。但胼胝体前部胶质瘤以高级别胶质瘤为主,总体预后较差。Objective To analyze pathological features and the corpus callosum front of glioma patients and its prognosis. Methods security of the application of microsurgical treatment on the 26 patients with corpus callosum front glioma in our hospital from January 2008 to December 2010 were selected for the study, and all the clinical data of patients were regressively analyzed. The patients were randomly divided into the microsurgical resection treatment group （observation group） with 12 cases, as well as traditional surgical treatment group （control group） with 12 cases, the effectiveness were comparatived. Results Clinical manifestations of patients with corpus callosum front of glioma were intracranial hypertension, cognitive dysfunction, epilepsy and other symptoms. By imaging diagnosis, 8 patients with lesions confined to the corpus callosum, 11 patients with the violation of the the frontal lobe, 3 patients with the lesion violations of the lateral wall, and violations of the limbic system of brain tissue in 2 patients, 2 patients with parietal violations. The patients blood loss, the average operation time, average length of stay were significantly better than the control group （P〈0.05）. Patients with high-grade gliomas were significantly more than in patients with low-grade gliomas （P〈0.05）. Conclusion For the front of the corpus callosum glioma patients ,mierosurgical resection of the tumor can be effective in reducing blood loss, shorter hospital stay and improve the quality of life of patients. Corpus callosum front of glioma is mainly high-grade gliomas, the overall prognosis is poor.

关 键 词：胼胝体前部胶质瘤 显微手术 可行性 

分 类 号：R739.4[医药卫生—肿瘤]