肾脏平滑肌瘤1例及临床病理分析  

Renal leiomyoma:A case report and clinicopathologic analysis

作　　者：刘立伟[1] 韩洪秀[1] 杜光烨[1] 陆玲娟[1] 董君波[1] 

机构地区：[1]上海交通大学医学院附属第三人民医院病理科,上海201900

出　　处：《现代肿瘤医学》2013年第11期2517-2519,共3页Journal of Modern Oncology

摘　　要：目的:报道1例起源于肾脏血管的肾脏平滑肌瘤,结合文献探讨其临床及病理组织学特点。方法:对1例肾脏平滑肌瘤进行大体检查、常规病理、免疫组化分析。结果:大体观察:肿瘤境界清楚,切面灰白色,均质实性,质地柔韧,无出血及坏死。显微镜下可见肿瘤由分化好的梭形细胞呈编织状排列。免疫组化:瘤细胞SMA+,desmin+,Vimentin+,NSE-,Bcl-2-,CD117-,S-100-,CD34-。结论:来源于肾脏小静脉血管壁的肾脏平滑肌瘤十分罕见,仅依赖临床病史及影像学很难做出明确诊断,病理学检查则弥补了二者的不足。肾脏平滑肌瘤需与肾血管平滑肌脂肪瘤、神经纤维瘤、平滑肌肉瘤、间质瘤、孤立性纤维性肿瘤、肾细胞癌等相鉴别。Objective：To report a case of renal leiomyoma originating from renal blood vessels and study its clinical and histopathological features with literature review.Methods：A renal leiomyoma was analyzed by general examination,conventional pathology and immunohistochemistry.Results：Macroscopically the tumor was well-defined,and the cut surface was grey,with a solid and elastic consistence,no hemorrhage or necrosis.Microscopically the tumor consisted of well-differentiated spindle cells which were arranged in interlacing fascicles.The tumor cells were immunostained with antibodies against SMA,desmin and Vimentin,while they were not immunostained with antibodies against NSE,Bcl-2,CD117,S-100 or CD34.Conclusion：Leiomyomas of renal vein are rare.Clinical history and radiological examinations are not sufficient for its clear diagnosis,while pathological examination is still possible.And it should be differentiated from renal angiomyolipoma,neurofibroma,leiomyosarcoma,interstitial tumor,solitary fibrous tumor and so on.

关 键 词：肾脏平滑肌瘤 病理组织学 肾静脉 

分 类 号：R737.11[医药卫生—肿瘤]