机构地区:[1]温州医学院附属第二医院眼科,325000 [2]温州市中医院眼科 [3]温州医学院附属第二医院放射科
出 处:《中华医学杂志》2013年第41期3280-3283,共4页National Medical Journal of China
基 金:浙江省科技厅项目基金(20LOC33013)
摘 要:目的评估调节发生时晶状体的形态变化。方法2011年1至6月在温州医学院在校生健康人中抽取符合入选标准的20~24岁受试志愿者30名30只眼,使用核磁共振成像(MRI)获得正常眼球调节放松时和调节紧张时晶状体形态图片,选取最佳横断面图片经Autocad2010软件处理,得到调节前后时的晶状体前后横截面积及总面积(CSA)、前房深度、晶状体厚度、晶状体直径、晶状体前后弧长、晶状体前后曲率半径、玻璃体腔径和眼轴的数值,采用配对设计t检验分析。结果调节放松时前曲率半径、后曲率半径、前截面积、后截面积、总截面积的数值分别为(8.7±0.8)mm,(6.2±0.5)mm,(7.5±2.1)mm^2,(12.0±2.6)mm^2,(20±4)mm^2;调节紧张时分别为(7.1±1.3)mm,(5.6±0.5)mm,(14.7±2.9)mm^2,(12.2±2.1)mm^2,(27±4)mm^2。调节发生时,前截面积(t=-15.653,P〈0.01)和总截面积(t=-11.556,P〈0.01)均增加,后截面积保持不变(t=-0.437,P〉0.05)。调节前后,前房深度(t=4.366,P〈0.01)、晶状体厚度(t=4.597,P〈0.01)、晶状体直径(t=-5.456,P〈0.01)差异有统计学意义,玻璃体腔径(t=0.428,P〉0.05)和眼轴(t=0.418,P〉0.05)差异无统计学意义。结论当调节发生时,前房深度变浅,晶状体厚度变厚,晶状体直径缩短,晶状体前截面积及总面积增加,晶状体后截面积、玻璃体腔径、眼轴均无明显改变。前截面积的变化提示调节与晶状体前囊特性、晶状体物质、核位置、睫状小带位置有关;倾向支持Helmholtz理论。Objective To evaluate the effects of accommodation on lens morphological characters. Methods From January 2011 to June 2011, magnetic resonance images of eyes were acquired from 30 subjects aged 20 to 24 years during accommodation and at rest. The optimal images were analyzed by Autocad 2010 to obtain the total lens cross-sectional area (CSA) and CSA of anterior and posterior portions of lens, anterior chamber depth, lens thickness, lens diameter, vitreous chamber depth and axial length during accommodation and at rest. Paired-t test was performed. Results The anterior curvature radius (mm), posterior curvature radius ( mm), CSA of anterior portion ( mm2 ), CSA of posterior portion (mm2), total lens CSA (mm2) was (8. 7 ±0. 8), (6. 2 ±0. 5), (7. 5 ±2. 1), (12. 0 ±2. 6), (20 ±4) during relaxed accommodation; anterior curvature radius (mm), posterior curvature radius (mm), CSA of anterior portion ( mm2 ), CSA of posterior portion ( mm2 ), total lens CSA ( mm2 ) was ( 7.1 ± 1.3 ), ( 5.6 ± 0. 5 ), ( 14. 7 ± 2. 9 ), ( 12. 2 ± 2. 1 ) and ( 27 ± 4 ) during accommodation. The total lens CSA ( t = -11. 556, P 〈 0.01 ) and CSA of anterior portion (t = - 15. 653, P 〈 0.01 ) both increased in accommodative states. The CSA of posterior portion of lens ( t = - 0. 437, P 〉 0. 05 ) under a statistically independent accommodative state. There was significant difference in the anterior chamber depth (t = 4. 366, P 〈 0. 01 ), lens thickness ( t = - 5. 456, P 〈 0. 01 ) and lens diameter ( t = 4. 597, P 〈 0.01 ) in accommodative states. There were insignificant differences both in vitreous chamber depth ( t = 0. 428, P 〉 0.05 ) and axial length ( t = 0. 418, P 〉 0. 05 ) under accommodative states. Conclusion During accommodation, the anterior chamber depth decreases, lens thickness increases and diameter of lens decreases while anterior portions and total lens CSA increase. There are insignifica
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...