Ⅲ期青年胃癌生存分析  

Survival analysis for young patients with phase Ⅲ gastric cancer

作　　者：徐丽华[1] 陈素秀[1] 蒋亦燕[1] 王红[2] 

机构地区：[1]温州医科大学附属第一医院全科医学科,浙江温州325000 [2]温州医科大学附属第二医院风湿免疫科,浙江温州325027

出　　处：《温州医学院学报》2013年第10期664-667,共4页Journal of Wenzhou Medical College

基　　金：温州市科技局科研基金资助项目(Y20120226)

摘　　要：目的:探讨与治疗相关的影响青年胃癌生存的独立预后因素。方法:对78例年龄≤40岁,手术分期Ⅲ期的青年胃癌患者进行生存分析。结果:1、3、5年生存率分别为80.8%、34.6%、9.6%,中位生存时间为28个月,中位无疾病进展时间为14个月;多因素分析表明阴性淋巴结数、化疗次数、中草药治疗是影响预后的独立因素。结论:阴性淋巴结个数>15、化疗次数≥6、中草药治疗能使Ⅲ期青年胃癌患者延长生存期,多学科合作、规范化和个体化的治疗,是提高胃癌患者生存率的关键。Objective：To identify the independent factors related to treatment on patients with gastric cancer.Methods：78 young patients not older than 40 with phase Ⅲ gastric cancer were studied by survival analysis.Results：Of the 78 cases,one-year survival rate was 80.8％,three-year survival rate was 34.6％,five-year survival rate was 9.6％,median survival time was 28 months,the median progression free survival was 14 months.The multivariate analysis showed that the number of lymph nodes with negative,the course of chemotherapy treatment,herb therapy were the independent prognostic factors.Conclusion：The number of lymph nodes with negative ＞15,the course of chemotherapy treatment ≥ 6 and herb therapy is benefit for the OS of young patients with gastric cancer,therefore,the treatment of multidisciplinary cooperation,normalization and individualization play a key role in improving the survival rate of patients with gastric cancer.

关 键 词：胃肿瘤 青年 生存分析 

分 类 号：R735.2[医药卫生—肿瘤]