重型颅脑损伤患者超早期行肠内营养支持的效果分析  

Clinical research on super early enteral nutrition support in patients with severe craniocerebral injury

作　　者：姚珍莹[1] 

机构地区：[1]灵山县人民医院神经外科,广西535400

出　　处：《中国临床新医学》2013年第9期854-857,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西钦州市科学研究与技术开发计划项目(编号:20126205)

摘　　要：目的探讨重型颅脑损伤患者超早期行肠内营养支持的治疗效果。方法将60例患者按住院单双号分为治疗组和对照组,每组30例,对照组采用常规支持治疗,治疗组于超早期行肠内营养支持治疗,观察比较两组疗效、血生化指标、并发症和预后等情况。结果治疗3周后对患者进行检查,治疗组的体重(BW)、肱三头肌皮皱厚度(TSF)、上臂肌围(AMC)、平衡NB(g/d)的减少值均大于对照组(P<0.05),治疗组的血清白蛋白、血红蛋白、血清前白蛋白及格拉斯哥昏迷指数(GOS)评分均高于对照组(P<0.05),治疗组消化道出血的发生率和病死率均低于对照组(P<0.01或<0.05)。结论重型颅脑损伤患者超早期行肠内营养支持可以改善氮平衡,改善患者营养状况,有利于神经功能缺损的康复和骨骼肌的合成,提高机体的免疫力,从而降低消化道出血率和病死率,值得临床推广应用。Objective To explore the early effect of super early enteral nutrition support in patients with severe craniocerebral injury.Methods According to the hospitalized single or double number,60 patients were divided into treatment group and control group,30 patients in each group.the control group with was treated conventional therapy.The treatment group received supwer early enteral nutrition support,the efficacy of blood biochemical indicators,complications and prognosis were observed and compared.Results At third week after treatment,the dicreased values in body weight（BW）,triceps skinfold（TSF）,arm muscle circumference（AMC）,NB（g / d） in the treatment group were less than those control group（P 0.05）.The levels of albumin,hemoglobin serum protein and the GOS scores in the treatment group were higher than those in the control group（P 0.05）,the incidence in pulmonary infection,abdominal distension,diarrhea,gastrointestinal bleeding and the mortality rates in the treatment group were lower than those in the control group（P 0.01 or P 0.05）.Conclusion For patients with severe craniocerebral injury,super early enteral nutrition support can promote recovery,improve nitrogen balance and the nutritional status of the patients,help neural function defect rehabilitation and synthesis of skeletal muscle,improve immunity,thereby reducing the pulmonary infection and other complications,reducing the mortality rate.

关 键 词：重型颅脑损伤 超早期肠内营养 

分 类 号：R74[医药卫生—神经病学与精神病学]