50例半肝切除治疗肝门部胆管癌的疗效观察  

Research in the treatment of hilar cholangiocarcinoma with hemihepatectomy in 50 cases

作　　者：于伟勇[1] 赵耀[1] 何敬东[1] 陈小飞[1] 喻晓娟[1] 

机构地区：[1]江苏省淮安市第一人民医院肿瘤内科,223300

出　　处：《重庆医学》2013年第31期3773-3775,共3页Chongqing medicine

摘　　要：目的总结不同手术方式对肝门部胆管癌患者治疗的临床及随访结果,探讨肝门部胆管癌临床治疗中的关键技术及相关预后。方法对50例肝门部胆管癌患者采用不同的手术方式,其中31例患者采用胆道联合局部肝切除术(对照组),19例患者采用半肝切除(观察组),对两组患者根治性切除率和生存率进行比较。结果两组患者根治性切除率分别为35.48%(11/31)和68.42%(13/19),差异有统计学意义(P=0.014),观察组1、3、5年生存率分别为85.4%,58.6%,32.2%;对照组分别为86.1%,65.2%,20.0%,差异有统计学意义(P=0.03)。结论根治性切除是患者获得治愈和长期生存最重要的措施,手术技巧的改进和经验的积累,联合半肝切除可以使肝门部胆管癌得切除率及根治率得到大幅度的提高,改善了肝门部胆管癌的预后。Objeetive To compare the clinical and follow-up results of different ways of operation for the treatment of patients with hilar cholangiocarcinoma,and to explore its e key technology and related prognosis. Methotls 31 out of 50 patients with biliary and partial liver resection（control group）, 19 patients with hemihepatectomy （observation group）. Radical resection rate and surviv- al rate were compared in the two groups. Results radical resection rate control group and observation group was 35.48% （11/31） and 68.42 % （13/19）, the difference was statistically significant（P= 0. 014） ;the difference of 1,3,5 year survival rates between the two groups were statistically significant （P = 0.03 ）, observation group = 85.4 %58. 6 %, 32.2 %, control group ： 86.1 %, 65.2 %, 20.0%. Conclusion Radical resection is still the most important measures the patients for cure and long-term survival, radical re- section rate,survival rate,and prognosis could be improved greatly by improving operation skills and experience accumulation,com- bined with hepatectomy.

关 键 词：胆管肿瘤 肝门 外科手术 疗效 

分 类 号：R735.8[医药卫生—肿瘤]