基因多态性与前列腺癌易患性的研究进展  

Research Progress in Relationship between Gene Polymorphisms and Genetic Susceptibility to Prostate Cancer

作　　者：骆强翔[1] 李炳坤[1] 

机构地区：[1]南方医科大学珠江医院泌尿外科,广州510280

出　　处：《医学综述》2013年第21期3888-3891,共4页Medical Recapitulate

摘　　要：前列腺癌是男性泌尿生殖系统最常见的恶性肿瘤。越来越多的研究表明,遗传因素是其发病的最重要的危险因素之一。目前,已有大量的研究中心开展基于基因多态性与前列腺癌易患性的基础与临床研究。大多数学者针对单一基因开展研究,且研究结果不尽相同。如果某种或某些基因的多态性与前列腺癌发病风险之间的关系被证实,将为基于基因水平的前列腺癌防治提供广阔的思路。Prostate cancer is the most common malignant tumor in male reproductive system. Multiple lines of evidence support genetics is one of the most important determining risk factors for prostate cancer. In recent years ,several works based on the basic and clinical studies of genetic have proposed susceptibility genes for prostale cancer, while most of them referred to the single gene. Meanwhile, the research results obtained were somewhat diverse. If the correlation between gene polymorphisms and prostate cancer is confirmed,it will provide a reference for prevention and treatment of prostate cancer based on the genetic level.

关 键 词：基因 多态性 前列腺癌 易患性 

分 类 号：R737.25[医药卫生—肿瘤]