常规肿瘤标志物在罗氏E411和E601两个检测系统之间的比对分析  

The Comparative Analysis of Conventional Tumor Markers in the Two Detection Systems between Roche E411 and E601

作　　者：唐妮娜[1] 

机构地区：[1]江苏省泰州市中医院检验科,225300

出　　处：《医学理论与实践》2013年第21期2823-2824,2827,共3页The Journal of Medical Theory and Practice

摘　　要：目的:探讨罗氏Cobas E411与Cobas E601两台电化学发光免疫分析仪检测结果的可比性。方法:参考美国临床和实验室标准协会(CLSI)EP9-A2文件,以E411为比对方法(X),E601为实验方法(Y),检测患者样本中甲胎蛋白(AFP)、癌胚抗原(CEA)、糖类抗原125(CA125)、糖类抗原199(CA199)的含量,并对实验数据进行比对分析。结果:两系统之间的相关性好,在医学决定水平处的预期偏倚均可接受。结论:使用不同检测系统检测同一项目时,应进行比对分析和偏倚评估,以保证系统间检测结果的可比性。Objective： To investigate the comparability of test results of two electrochemiluminescence immunoassay analyzer between Roche Cobas E411 and Cobas E601. Methods： According to United States Clinical and Laboratory Standards Institute （CLSI） EP9-A2 document, E411 was acted as comparison method （X） and E601 was as the experi- mental method （Y）. Alpha fetoprotein （AFP）, carcinoembryonic antigen （CEA）, carbohydrate antigen 125 （CA125） and carbohydrate antigen 199 （CA199） levels of patient samples were tested and the results were analyzed. Results： The correlation between the two systems is good and the bias is acceptable in the medical decision level. Conclusion： The comparative analysis and bias evaluation systems should be carried out to ensure the comparability of test results when the same items are detected with different detection systems.

关 键 词：E411 E601 肿瘤标志物 比对分析 

分 类 号：R730.43[医药卫生—肿瘤]