NSAIDs胃病51例的内镜特点及临床分析  

Analysis of clinical and endoscopic characteristics in 51 cases with NSAIDs gastropathy

作　　者：王昌雄[1,2] 徐美东[3] 王济纬[1,2] 朱雅碧[1,2] 王立明[1,2] 

机构地区：[1]浙江省丽水市人民医院 [2]温州医学院附属六院消化内镜治疗中心,浙江丽水323000 [3]复旦大学附属中山医院内镜中心,上海200032

出　　处：《中国现代医生》2013年第33期156-158,共3页China Modern Doctor

基　　金：浙江省医学会临床科研资金项目(2011ZYC-A123)

摘　　要：目的为正确诊治NSAIDs胃病提供临床资料。方法回顾性分析2011年1月～2012年12月我院51例NSAIDs胃病的临床及内镜特点。结果识别NSAIDs胃病的内镜下表现特点,其发生与溃疡危险因素呈正相关,既往有消化性溃疡或出血患者为本病的高危人群。结论消化科医师应准确识别NSAIDs胃病的内镜下表现特点,建议NSAIDs应给予最小的有效治疗量,并及时监测血常规、大便潜血及行胃镜检查,对伴溃疡危险因素患者可同时预防性应用PPI及胃黏膜保护剂,以积极应对该类药物引起的不良反应。Objective To provide clinical data for proper diagnosis and treatment of NSAID gastropathy. Methods Fifty-one patients with NSAID gastropathy were evaluated in our hospital from January 2011 to December 2012. The clinical data and endoscopic features were analyzed respectively. Results The features of NSAIDS gastropathy were correctly identified under direct endoscopic visualization. Its occurrence was positively associated with the risk factors for digestive ulcer,patients with a history of peptic ulcer or bleeding at high risk for the disease. Conclusion Gas- troenterologists should correctly recognize the endoscopic features of NSAID gastropathy. We suggest that NSAIDs should be administered with minimum effective dosage. Patients should be monitored appropriately with blood cell count, fecal occult blood test and endoscopy. For patients with risk factors of digestive ulcer, PPI and mucosal protec- tive agent can be administered simuhaneously in order to avoid the side-effects of NSAIDs.

关 键 词：NSAIDS药物 NSAIDs胃病 内镜下表现 临床特点 

分 类 号：R573[医药卫生—消化系统]