27例成人烟雾病的临床特点分析  

Clinical study in twenty-seven patients with moyamoya disease

作　　者：王晓龙[1] 张尊胜[1] 程言博[1] 

机构地区：[1]江苏徐州医学院附属医院神经内科,221002

出　　处：《中华脑血管病杂志（电子版）》2013年第4期26-28,共3页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

摘　　要：目的探讨成人烟雾病患者的临床特点，以提高对烟雾病的认识。方法回顾徐州医学院附属医院神经内科2010年1月～2011年12月收治的27例初次诊断烟雾病住院患者的临床资料，分析烟雾病的发病年龄、性别和伴发疾病的特点。结果本组患者发病平均年龄39．2岁，其中男性患者为33．6岁，女性为41．5岁，不同性别患者组发病年龄比较差异无显著性；不同性别患者间临床表现分布无显著性差异；男女患者比例1：2．38，发病频数分布拟合优度检验差异具有显著性（x2=4．481，P=0．034）；患者起病形式为缺血性卒中表现者占59．25％；本组中3例累及椎基底动脉系统，占11．11％；40．74％患者合并高血压。结论本组成人烟雾病患者中女性患者比例高于男性，多数患者临床表现为缺血性脑卒中。该病受累血管可以合并椎一基底动脉系统。Objective To analyze the clinical manifestations of adult moyamoya disease （MMD）. Methods The records of all 27 consecutive MMD patients from January, 2010 to December, 2011 in neurology department of our hospital were reviewed. The data of age, gender, and onset symptoms were analyzed. Results In this group, the overall average onset age was 39.2 years, 33.6 years for male patients and 41.5 years for females. There was no significant different in onset age between male and female groups, and also no significant different in clinical manifestation pattern. Ratio of male to female was 1：2.38, goodness of fit Chi-square test of the incidence frequency distribution show a significant different （X 2--4.481, P=0.034）. 59.25% patients developed ischemic stroke as the major onset symptom. Three （11.11%） of all the patients were vertebral basilar artery involved; 40.74% patients complicated with hypertension. Conclusion In this adult MMD group, the ratio of females is higher than males, and major patients manifested ischemic stroke symptoms. Vertebral basilar artery system can also be involved in this disease.

关 键 词：成人 烟雾病 回顾分析 

分 类 号：R743.3[医药卫生—神经病学与精神病学]