中药干预提高进展期胃癌生存期及生存质量的临床研究  

Clinical research on intervention of traditional Chinese medicine in improving the survival time and life quality for advanced gastric cancer

作　　者：袁彬 褚亮 张恩[2] 乔惠萍[3] 施常备 

机构地区：[1]陕西省肿瘤医院,陕西西安710061 [2]陕西省人民医院,陕西西安710062 [3]陕西省宝鸡市中医医院,陕西宝鸡712000

出　　处：《现代中西医结合杂志》2013年第33期3649-3650,3653,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：陕西省中医药管理局课题(1c63)

摘　　要：目的观察中药干预对进展期胃癌患者生存期和生活质量的影响。方法采用平行随机双盲的方法,将200例患者分为2组,对照组采用XELOX方案化疗,观察组采用中药联合XELOX方案治疗。观察2组患者疗效、生存期和生活质量。结果观察组不良反应发生率显著低于对照组(P<0.05)。2组生活质量评分比较有显著性差异(P<0.05)。观察组1 a、2 a生存率显著高于对照组。观察组近期缓解率略高于对照组,但无显著性差异(P>0.05)。结论加用中药干预可明显改善进展期胃癌患者的生活质量,延长其生存期。Objective It is to observe the influence of intervention of traditional Chinese medicine （TCM） on the survival time and life quality of patients with advanced gastric cancer （ AGC ）. Methods 200 patients were randomly divided into observed group and control group with the way of randomized and parallel-control. The patients were treated with chemotherapeutic schedule of XELOX simply in control group and with TCM plus XELOX in observed group. The clinical effect, survival time and life quality were observed in both groups. Results The rate of adverse reaction in observe group was markedly lower than that in control group （P 〈 0.05）. There was significant difference in life quality between two groups （ P 〈 0.05 ）. The survival rate of 1 - or2 - year in observe group was markedly higher than that in control group （ all P 〈 0.05 ）. There was no significant difference in recent remission rate between both groups （ P 〉 0.05 ）. Conclusion TCM intervention can obviously improve the life quality of patients with AGC, and extend their survival time.

关 键 词：中医药 进展期胃癌 生存期 生活质量 

分 类 号：R735.2[医药卫生—肿瘤]