Bilayer self-assembly on a hydrophilic, deterministically nanopatterned surface  

作　　者：Gregory S. Smith Seung-Yong Jung James F. Browning Jong K. Keum Nickolay V. Lavrik Mussie G. Alemseghed C. Patrick Collier 

机构地区：[1]Biology and Soft Matter Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA [2]Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA [3]Chemical and Engineering Materials Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA [4]Department of Chemical and Materials Engineering, University of Cincinnati, Cincinnati, OH 45221-0012, USA

出　　处：《Nano Research》2013年第11期784-794,共11页纳米研究（英文版）

摘　　要：We present measurements of the in situ, microscopic architecture of a self- assembled bilayer at the interface between a regularly nanopatterned surface and an aqueous sub-phase using neutron reflectometry. The substrate is patterned with a rectangular array of nanoscale holes. Because of the high quality of the pattern, using neutron reflectometry, we are able to map the surface-normal density distribution of the patterned silicon, the penetration of water into the pattern, and the distribution of a deposited film inside and outside of the etched holes. In this stud; 1,2-dilauroyl-sn-glycero-3-phosphocholine （DLPC） single bilayers were deposited on the hydrophilic patterned surface. For bilayers deposited either by vesicle fusion （VF） or by the Langmuir-Schaefer （L-S） technique, the most consistent model found to fit the data shows that the lipids form bilayer coatings on top of the substrate as well as the bottoms of the holes in an essentially conformal fashion. However, while there is a single bilayer on the unetched silicon surface, the lipids coating the bottoms of the holes form a complex bimodal structure consistent with a rough surface produced by the etching process. This study provides insight into film transfer both outside and inside regular nanopatterned features.我们现在的大小在里面 situ，在接口在之间的自我装配的 bilayer 的显微镜的建筑学一定期用中子反射计的 nanopatterned 表面和一个水的亚阶段。底层与 nanoscale 洞的一个矩形的数组是有图案的。因为模式的高质量，用中子反射计，我们能印射有图案的硅，进模式的水的穿入，和一部扔的电影的分发的表面正常密度分发在内并且在蚀刻的洞外面。在这研究， 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC ) 单身者 bilayers 在吸水的有图案的表面上被扔。为泡熔化(VF ) 或由 Langmuir-Schaefer (L-S ) 技术扔的 bilayers，发现适合数据的最历久不渝的模型证明类脂化合物以一种实质上保角的方式象洞的底部一样在底层上形成 bilayer 涂层。然而，当 unetched 硅上有单个 bilayer 时，出现，与不平的表面一致的复杂 bimodal 结构由蚀刻生产了的洞形式的底部处理的类脂化合物涂层。这研究在外面并且在常规 nanopatterned 特征内提供卓见进电影转移。

关 键 词：thin film NANOPATTERN neutron reflectivity LIPID SELF-ASSEMBLY 

分 类 号：TN304.12[电子电信—物理电子学] TQ028.8[化学工程]