术中腹腔游离胃癌细胞检测与胃癌临床特点的相关性研究  

Correlative study of intraoperative intraperitoneal free cancer cell detection and clinical characteristics of gastric carcinoma

作　　者：马赞林[1] 李海[1] 白少军[1] 余建军[1] 

机构地区：[1]宁夏医科大学总医院外科,宁夏银川750004

出　　处：《宁夏医学杂志》2013年第10期898-900,共3页Ningxia Medical Journal

摘　　要：目的通过对术中胃癌腹腔游离癌细胞检测,探讨其与胃癌临床特点的相关性。方法用赛涂液基薄层细胞制片术对40例进展期胃癌患者进行胃切除术前腹腔游离癌细胞的检测,分析其与临床特点的相关性。结果 40例胃癌腹腔游离癌细胞的阳性率为47.5%(19/40),肿瘤>6 cm、浆膜受侵、淋巴结转移、病理分化程度低等的腹腔游离癌细胞的检出率明显高于对照组,差异有统计学意义(P<0.05)。结论术中检测腹腔游离癌细胞有助于评价手术效果,判断预后以及为辅助治疗提供依据。Objective To explore the correlation of intraperitoneal free cancer cells （IFCCS） and clinical characteristics. Methods IFCCS of 40 gastric cancer patients being operated under Cytoscreen System were prospectively analyzed to assess its relation with clinical characteristics. Results The overall positive rate of IFCCS was 47.5%. There was statistical significant parameters between IFCCS and tumor size, serosal invasion, abdominal lymph node metastasis and pathological stage （ P 〈 0.05 ）. Conclusion Tumor size 〉 6 cm, serosal invasion, abdominal lymphnode metastasis and low pathological stage have correlation with IFCCS. IFCCS would predict the prognosis and provide information for further adjuvant therapy.

关 键 词：腹腔游离癌细胞 淋巴结转移 胃癌 

分 类 号：R735.2[医药卫生—肿瘤]