成年人复发性阿弗他溃疡致病相关因素分析  

Pathogenic factors of recurrent aphthous ulcer in adults

作　　者：买迁 赵蕊[2] 王婧娇[3] 张新[4] 漆明[3] 

机构地区：[1]宁夏医科大学研究生学院,银川750004 [2]河北省老年病医院口腔科,石家庄050011 [3]宁夏医科大学总医院口腔科,银川750004 [4]宁夏回族自治区人民医院口腔科,银川750004

出　　处：《重庆医科大学学报》2013年第11期1389-1392,共4页Journal of Chongqing Medical University

基　　金：宁夏卫生厅重点科研计划资助项目(编号:2011040)

摘　　要：目的:通过对复发性阿弗他溃疡(recurrent aphthous ulcer,RAU)的致病相关因素进行调查,筛选出该病的主要致病相关因素。方法:采用自编的《RAU致病因素调查问卷》进行调查,使用非条件logistic回归分析对各个相关因素进行统计。结果:引入回归方程的相关高危因素为:消化系统慢性疾病、精神压力、喜吃辣食、家族史、便秘、指数、吸烟指数和喜吃酸食,后两者的回归系数<0,OR值<1。经Spearman秩相关分析,RAU的发生与吸烟指数呈负相关(r s=-0.170,P=0.000),与指数呈正相关(r s=0.133,P=0.000)。结论:引起RAU发生的危险因素由大到小为:消化系统慢性疾病、精神压力、喜吃辣食、家族史、便秘和指数;吸烟和喜吃酸食可能会减轻RAU的发生。Objective ：To explore the main risk factors of recurrent aphthous ulcer（RAV） by investigating its pathogenic factors. Meth- ods：Using the self-made questiomtaire ofRA U＇s risk factors to do the investigation. The high-risk factors of RAU were screened out from all correlative factors by non-conditional logistic regression analysis. Results：The high-risk factors including chronic digestive system disease,mental pressure,liking spicy food ,family history, constipation, calculus index, smoking index and liking acidic food were introduced in the regression equation. OR values and regression coefficient of smoking index factor and liking acidic food fac- tor were less than 1 and 0, re spectiuely （P〈0.05）. RAU and smoking index showed a negative correlation （rs=-0.170,P=0.000） while RAU and calculus index showed a positive correlation（rs=0.133,P=-0.000） based on Spearman rank correlation analysis. Conclusions： These pathogenic factors from high-risk to low-risk were chronic digestive system disease, mental pressure, liking spicy food ,family history, constipation and calculus index. Smoking and liking for acidic food may be the protective factors of RAU.

关 键 词：复发性阿弗他溃疡 致病相关因素 LOGISTIC回归分析 

分 类 号：R781.5[医药卫生—口腔医学]